Fernandez-Busnadiego, Ruben

Authors Reshetniak S, Bogaciu CA, Bonn S, Brose N, Cooper BH, D’Este E, Fauth M, Fernández-Busnadiego R, Fiosins M, Fischer A, Georgiev SV, Jakobs S, Klumpp S, Köster S, Lange F, Lipstein N, Macarrón-Palacios V, Milovanovic D, Moser T, Müller M, Opazo F, Outeiro TF, Pape C, Priesemann V, Rehling

Authors Brücke C, Al-Azzani M, Ramalingam N, Ramón M, Sousa RL, Buratti F, Zech M, Sicking K, Amaral L, Gelpi E, Chandran A, Agarwal A, Chaves SR, Fernández CO, Dettmer U, Lautenschläger J, Zweckstteter M, Fernandez Busnadiego R, Zimprich A, Outeiro TF Journal MedRxiv Citation medRxiv 2024.09.23.24313864. Abstract Background: Parkinson’s

Authors Hickey KL, Panov A, Whelan EM, Schäfer T, Mizrak A, Kopito RR, Baumeister W, Fernández-Busnadiego R, Harper JW Journal BioRxiv Citation bioRxiv 2024.08.30.610524. Abstract A hallmark of neurodegenerative diseases is the progressive loss of proteostasis, leading to the accumulation of misfolded proteins or protein aggregates, with subsequent cytotoxicity. To

Authors Wagner J, Carvajal AI, Bracher A, Beck F, Wan W, Bohn S, Körner R, Baumeister W, Fernandez-Busnadiego R, Hartl FU Journal Nature Citation Nature. 2024 Aug 21. Abstract Chaperonins are large barrel-shaped complexes that mediate ATP-dependent protein folding1-3. The bacterial chaperonin GroEL forms juxtaposed rings that bind unfolded protein

Authors Schulte T, Chaves-Sanjuan A, Speranzini V, Sicking K, Milazzo M, Mazzini G, Rognoni P, Caminito S, Milani P, Marabelli C, Corbelli A, Diomede L, Fiordaliso F, Anastasia L, Pappone C, Merlini G, Bolognesi M, Nuvolone M, Fernández-Busnadiego R, Palladini G, Ricagno S Journal Nature Communications Citation Nat Commun. 2024

Authors Raimi OG, Ojha H, Ehses K, Dederer V, Lange SM, Rivera CP, Deegan TD, Chen Y, Wightman M, Toth R, Labib KPM, Mathea S, Ranson N, Fernández-Busnadiego R, Muqit MMK Journal Science Advances Citation Sci Adv. 2024 Jun 7;10(23):eadn7191. Abstract Loss-of-function mutations in PTEN-induced kinase 1 (PINK1) are a

Authors Zung N, Aravindan N, Boshnakovska A, Valenti R, Preminger N, Jonas F, Yaakov G, Willoughby M, Homberg B, Keller J, Kupervaser M, Dezorella N, Dadosh T, Wolf SG, Itkin M, Malitsky S, Brandis A, Barkai N, Fernandez-Busnadiego R, Reddi A, Rehling P, Rapaport D, Schuldiner M Journal BioRxiv Citation

Authors Keller J, Fernández-Busnadiego R Journal Current Opinion in Cell Biology Citation Curr Opin Cell Biol. 2024 Apr 26;88:102363. Abstract Cryo-electron tomography (cryo-ET) allows high resolution 3D imaging of biological samples in near-native environments. Thus, cryo-ET has become the method of choice to analyze the unperturbed organization of cellular membranes.

Authors Diep DTV, Collado J, Hugenroth M, Fausten RM, Percifull L, Wälte M, Schuberth C, Schmidt O, Fernández-Busnadiego R, Bohnert M   Journal Developmental Cell   Citation Dev Cell. 2024 Feb 16:S1534-5807(24)00036-4.   Abstract The lipid droplet (LD) organization proteins Ldo16 and Ldo45 affect multiple aspects of LD biology in

Authors Alfken J, Neuhaus C, Major A, Taskina A, Hoffmann C, Ganzella M, Petrovic A, Zwicker D, Fernández-Busnadiego R, Jahn R, Milovanovic D, Salditt T Journal European Physical Journey. E, Soft Matter Citation Eur Phys J E Soft Matter. 2024 Jan 25;47(1):8. Abstract We study the formation of vesicle condensates