Betz, TImo

Authors Vos BE, Vadapalli Y, Muenker TM, Astad Jentoft IM, Todisco E, Eskandari MA, Schuh M, Lenart P, Betz T Journal Biophysical Journal Citation Biophys J. 2025 Aug 18:S0006-3495(25)00524-7. Abstract The mechanical properties of the cytoplasm and nucleoplasm are crucial for the correct and robust functioning of a cell and

Authors Jurado A, Isensee J, Hofemeier A, Krüger LJ, Wittkowski R, Golestanian R, Bittihn P, Betz T Journal Biophysical Journal Citation Biophys J. 2025 Jul 22:S0006-3495(25)00450-3. Abstract The measurement of stresses and forces at the tissue level has proven to be an indispensable tool for the understanding of complex biological

Authors Jurado A, Isensee J, Hofemeier A, Krüger LJ, Wittkowski R, Golestanian R, Bittihn P, Betz T Journal Biophysical Journal Citation Biophys J. 2025 Jul 22:S0006-3495(25)00450-3. Abstract The measurement of stresses and forces at the tissue level has proven to be an indispensable tool for the understanding of complex biological

Authors Tiper Y, Xie Z, Hofemeier AD, Lad H, Luber M, Krawetz R, Betz T, Zimmermann WH, Morton AB, Segal SS, Gilbert PM. Journal American Journal of Physiology. Cell Physiology Citation Am J Physiol Cell Physiol. 2025 Feb 28. Abstract Skeletal muscle microtissues are engineered to develop therapies for restoring

Authors Eskandari MA, Fischer J, Veyret N, Marx D, Betz T Journal Arxiv Citation arXiv:2501.14538. Abstract While mechanobiology has demonstrated that precise control over mechanical properties at the whole-cell level is crucial for many biological functions, comparatively little attention has been paid to the intracellular mechanical properties. Experimental tools have

Authors Jimenez AJ, Isensee J, Hofemeier A, Krueger LJ, Wittkowski R, Golestanian R, Bittihn P, Betz T Journal BioRxiv Citation bioRxiv 2025.01.22.633835. Abstract The measurement of stresses and forces at the tissue level has proven to be an indispensable tool for the understanding of complex biological phenomena such as cancer

Authors Raj N, Weiss M, Vos BE, Weischer S, Brinkmann F, Betz T, Trappmann B, Gerke V Journal Advanced Science Citation Adv Sci (Weinh). 2024 Oct 3:e2402317. Abstract Disruptions of the eukaryotic plasma membrane due to chemical and mechanical challenges are frequent and detrimental and thus need to be repaired

Authors Muenker TM, Knotz G, Krüger M, Betz T Journal Nature Materials Citation Nat Mater. 2024 Jul 31. Abstract Living systems are complex dynamic entities that operate far from thermodynamic equilibrium. Their active, non-equilibrium behaviour requires energy to drive cellular organization and dynamics. Unfortunately, most statistical mechanics approaches are not

Authors Vos BE, Muenker TM, Betz T Journal Current Opinion in Cell Biology Citation Curr Opin Cell Biol. 2024 Jun 1;88:102374. Abstract Intracellular organization is a highly regulated homeostatic state maintained to ensure eukaryotic cells’ correct and efficient functioning. Thanks to decades of research, vast knowledge of the proteins involved

Authors Muenker TM, Vos BE, Betz T Journal eLife Citation eLife13:RP97416. Abstract Living cells are complex entities that perform many different complex tasks with astonishing robustness. While the direct dependence of biological processes on controlled protein expression is well established, we only begin to understand how intracellular mechanical characteristics guide