2026

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26.08.2026

Systematic Review and Transcriptomic Meta-analysis of Environmental Enrichment Reveal Core Molecular Programs of Brain Plasticity

Authors Kurowska M, Miozzo F, Schroeder R, Machnicka MA, Pérez-González R, Merienne K, Fischer A, Barco A, Boutillier AL, Wilczyński B Journal Molecular Neurobiology Citation Mol Neurobiol. 2026 Aug 26;63(1):857. Abstract Environmental enrichment (EE) paradigms in rodents have long demonstrated that enhanced sensory, cognitive, social, and motor stimulation positively impacts
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26.08.2026

In silico framework for benchmarking optogenetic hearing restoration

Authors Khurana L, Nejedly P, Zhang Y, Jagger DJ, Nogueira W, Moser T, Jablonski L Journal Journal of Neural Engineering Citation J Neural Eng. 2026 Aug 26. Abstract Objective: Cochlear implants (CI) partially restore hearing in profoundly hearing-impaired or deaf individuals by electrically stimulating the auditory nerve. A primary bottleneck
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22.08.2026

Distinct mitochondrial DNA single-nucleotide variant signatures in TOP3A-deficient cardiomyocytes

Authors Gaubert M, Alachram H, Gönenç II, Domínguez I, Argyriou C, Schmidt J, Kaulfuß S, Pavez-Giani M, Schott CT, Munk A, Zibat A, Cyganek L, Yigit G, Wollnik B Journal BioRxiv Citation bioRxiv 2026.08.18.745450. Abstract The human heart has a continuous and exceptionally high demand for energy, which is met
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18.08.2026

Dielectric Interfaces Reshape Dynamic Single-Molecule Optical Fingerprints in Nanoscopic Polymer Films

Authors Marx D, Malsbenden D, Gligonov I, Wöll D, Enderlein J, Nevskyi O Journal ChemRxiv Citation ChemRxiv. 18 August 2026. Abstract Fluorescence lifetimes near dielectric interfaces depend on molecular dipole orientation, but this relationship becomes more complex when emitters are confined within finite nanoscopic films. Here, we combine radially polarized
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14.08.2026

Adaptation of OXPHOS biogenesis to cellular requirements

Authors Dennerlein S, Rehling P Journal Protein Science Citation Protein Sci. 2026 Sep;35(9):e70763. Abstract Metabolic cues regulate the formation of the mitochondrial OXPHOS machinery. These regulatory processes are tightly linked to mitochondrial translation, proteolytic degradation of unassembled subunits, and the formation of supercomplexes, creating checkpoints at which nutrient availability, oxygen
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11.08.2026

Optimizing infectious disease mitigation under dynamic conditions

Authors Müller L, Sartori F, Dehning J, Eggl MF, Priesemann V Journal Proceedings of the National Academy of Sciences of the USA Citation Proc Natl Acad Sci U S A. 2026 Aug 11;123(32):e2527395123. Abstract Mitigation measures are essential for controlling the spread of infectious diseases during pandemics and epidemics, but
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11.08.2026

ONE microscopy

Authors Shaib AH, Alawieh MM, Rizzoli SO Journal Nature Protocols Citation Nat Protoc. 2026 Aug 11. Abstract The introduction of expansion microscopy (ExM), a decade ago, marked a shift in super-resolution imaging, by physically separating fluorophores to bypass the diffraction limit. Numerous ExM developments have extended the method’s reach since,
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06.08.2026

„Heart-in-the-dish“ models identify mechanisms of diastolic dysfunction

Authors Dittrich GM, Zimmermann WH. Journal Cell Stem Cell Citation Cell Stem Cell. 2026 Aug 6;33(8):1243-1245. Abstract Modeling of cardiac pathologies in tissue-engineered models is coming of age. Two independent studies by Reid et al.1 and Tani et al.2 present in-depth multi-phenomics data from a human cardiac organoid (hCO) model
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03.08.2026

A microfluidics platform for studying ion and solute transport by isolated synaptic vesicles

Authors Upmanyu N, Olsthoorn L, Leon S, Sambandan S, Perego E, Mimoso T, Socrier L, Cretich M, Chiari M, Steinem C, Köster S, Jahn R Journal Colloids and Surfaces B: Biointerfaces Citation Colloids Surf B Biointerfaces. 2026 Aug 3;268(Pt 2):116020. Abstract Loading of synaptic vesicles with neurotransmitters, an essential step
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31.07.2026

SGLT2 inhibition improves sarcomere contractile dysfunction in human models of dilated cardiomyopathy

Authors Plota D, Nosheen Saleem H, Lin KH, Wali R, Cheruiyot C, Münzel L, Hutschenreiter T, Tiburcy M, Meyer T, Habeck M, Wiedmann F, Schmidt C, Zimmermann WH, Ebert A Journal Journal of Translational Medicine Citation J Transl Med (2026). Abstract Background: Sodium–glucose cotransporter 2 inhibitors (SGLT2i) are now widely
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