2022

Authors Dullin C, Svetlove A, Zschüntzsch J, Alves F Journal Scientific Reports Citation Sci Rep. 2022 Aug 2;12(1):13299. Abstract Retrospective gating (RG) is a well established technique in preclinical computed tomography (CT) to assess 3D morphology of the lung. In RG additional angular projections are recorded typically by performing multiple

Authors Lange T, Backhaus SJ, Beuthner BE, Topci R, Rigorth KR, Kowallick JT, Evertz R, Schnelle M, Ravassa S, Díez J, Toischer K, Seidler T, Puls M, Hasenfuß G, Schuster A Journal Journal of Cardiovascular Magnetic Resonance Citation J Cardiovasc Magn Reson. 2022 Jul 28;24(1):45. Abstract Background: Since cardiovascular magnetic

Authors Kaiyrzhanov R, Perry L, Rocca C, Zaki MS, Hosny H, Araujo Martins Moreno C, Phadke R, Zaharieva I, Camelo Gontijo C, Beetz C, Pini V, Movahedinia M, Zanoteli E, DiTroia S, Vuillaumier-Barrot S, Isapof A, Mehrjardi MYV, Ghasemi N, Sarkozy A, Muntoni F, Whalen S, Vona B, Houlden H,

Authors Santos GL, DeGrave AN, Rehman A, Al Disi S, Xhaxho K, Schröder H, Bao G, Meyer T, Tiburcy M, Dworatzek E, Zimmermann WH, Lutz S Journal Biomaterials Advances Citation Biomater Adv. 2022 Jul 21:213041. Abstract Tissue engineering with human cardiac fibroblasts (CF) allows identifying novel mechanisms and anti-fibrotic drugs

Authors Seefelder M, Klein FAC, Landwehrmeyer B, Fernández-Busnadiego R, Kochanek S Journal Journal of Huntington’s Disease Citation J Huntingtons Dis. 2022 Jul 16. Abstract Since the discovery of the mutation causing Huntington’s disease (HD) in 1993, it has been debated whether an expanded polyglutamine (polyQ) stretch affects the properties of

Authors Wolf BJ, Kusch K, Hunniford V, Vona B, Kühler R, Keppeler D, Strenzke N, Moser T Journal EMBO Molecular Medicine Citation EMBO Mol Med. 2022 Jul 14:e15798. Abstract Hearing impairment, the most prevalent sensory deficit, affects more than 466 million people worldwide (WHO). We presently lack causative treatment for

Authors Farnung L, Ochmann M, Garg G, Vos SM, Cramer P Journal Molecular Cell Citation Mol Cell. 2022 Jul 13:S1097-2765(22)00610-4. Abstract During gene transcription, RNA polymerase II (RNA Pol II) passes nucleosomes with the help of various elongation factors. Here, we show that RNA Pol II achieves efficient nucleosome passage

Authors Lin KH, Taschenberger H, Neher E Journal Proceedings of the National Academy of Sciences Citation Proc Natl Acad Sci U S A. 2022 Aug 23;119(34):e2207987119. Abstract Glutamatergic synapses display variable strength and diverse short-term plasticity (STP), even for a given type of connection. Using nonnegative tensor factorization and conventional

Authors Lin SJ, Vona B, Porter HM, Izadi M, Huang K, Lacassie Y, Rosenfeld JA, Khan S, Petree C, Ali TA, Muhammad N, Khan SA, Muhammad N, Liu P, Haymon ML, Rüschendorf F, Kong IK, Schnapp L, Shur N, Chorich L, Layman L, Haaf T, Pourkarimi E, Kim HG, Varshney

Authors Koss DJ, Erskine D, Porter A, Palmoski P, Menon H, Todd OGJ, Leite M, Attems J, Outeiro TF Journal Acta Neuropathologica Communications Citation Acta Neuropathol Commun. 2022 Jul 6;10(1):98. Abstract Dementia with Lewy bodies (DLB) is pathologically defined by the cytoplasmic accumulation of alpha-synuclein (aSyn) within neurons in the