Latest Publications

Authors Pradhan R, Petrovic Z, Sadman Sakib M, Schröder S, Manfred Krüger D, Pena T, Diniz E, Burkhardt S, Schütz AL, Gisa V, Grzadzielewska I, Toischer K, Stein TD, Krzysztof Blusztajn J, Delalle I, Radulovic J, Sananbenesi F, Fischer A Journal Advanced Science (Weinheim) Citation Adv Sci (Weinh). 2026 Mar

Authors Folarin RO, Olopade FE, Gilbert TT, Ladagu AD, Dos Santos PIP, Mustapha OA, Kpasham LZ, Outeiro TF, Olopade JO Journal Metabolic Brain Disease Citation Metab Brain Dis. 2026 Mar 12;41(1):52. Abstract Vanadium, an environmental pollutant, is closely associated with neurodegeneration, primarily through oxidative damage and chronic neuroinflammation. While chronic

Authors Hamann TE, Wieland A, Mohseni F, Vukušić K, Tirincsi A, Wardenaar R, Losito M, Harmsen I, Gönenc II, Wollnik B, Foijer F, Tolić IM, Storchová Z, Räschle M Journal Nucleid Acid Research Citation Nucleic Acids Res. 2026 Feb 24;54(5):gkag199. Abstract The BLM helicase is a critical genome maintenance protein

Authors Müller GF, Göpel T, Scherf N, Huisken J. Journal Frontiers in Bioinformatics Citation Front Bioinform. 2026 Mar 10;6:1757489. Abstract Variation is a foundational biological principle that has historically been marginalized-both due to limited experimental accessibility and because of idealized, stereotypic blueprints rooted in essentialist thinking. With the advent of

Authors Martinez de Paz JM, Mayer JL, Wanken P, Rodrigues Apgaua B, Ablitip A, Behera L, Macé E Journal BioRxiv Citation bioRxiv 2026.03.06.710089. Abstract Arousal fluctuations during wakefulness have a major impact on physiology and behavior, including perception and task performance. Arousal is also known to be a strong modulator

Authors Ramakrishna V, Gollisch T Journal BioRxiv Citation bioRxiv 2026.03.06.710066. Abstract Photoreceptor degeneration is among the leading causes of blindness and optogenetics as a potential therapeutic measure has garnered much attention over recent years. In this approach, light-sensitive molecules like Channelrhodopsin-2 (ChR2) are inserted into neurons in the retina to

Authors Ehses K, López-Alonso JP, Antico O, Azem A, Muqit MMK, Ubarretxena-Belandia I, Fernández-Busnadiego R Journal Science Advances Citation Sci Adv. 2026. Sci Adv. 2026 Mar 6;12(10):eaed3579. Abstract Cells have evolved organelle-specific responses to maintain protein homeostasis (proteostasis). During proteostatic stress, mitochondria down-regulate translation and enhance protein folding, yet the

Authors Wanken P, Edelman BJ, Behera L, Martinez de Paz JM, McCarthy PT, Macé E Journal BioRxiv Citation bioRxiv 2026.03.06.709845. Abstract Animals exhibit behavior in the absence of external stimuli or explicit tasks. Is the initiation of such spontaneous behavior shaped by internal brain states in a predictable manner? If

Authors Kuhle B, Krebs L, Bhatta A, Dennerlein S, Rehling P, Hillen H Journal BioRxiv Citation bioRxiv 2026.03.02.709036. Abstract The non-templated addition of the 3′CCA end is the final universal step of tRNA maturation. In humans, 3′CCA addition on nuclear- (nu-tRNA) and mitochondria-encoded tRNAs (mt-tRNA) is catalyzed by a single

Authors Albert L, Basak S, Koerner H, Oleksiievets N, Mougios N, Cotroneo ER, Frei MS, Enderlein J, Broichhagen J, Simeth NA, Tsukanov R, Opazo F Journal BioRxiv Citation bioRxiv 2026.03.02.709025. Abstract Multiplexed fluorescence imaging is limited by spectral overlap, whereas fluorescence lifetime provides an orthogonal encoding dimension. We replace genetically