2024 – Seite 18

23.04.2024

Über Tierversuche sprechen

Mit Transparenz und Fakten einem emotionalen Thema begegnen Tierversuche in der Forschung sind ein Thema, bei dem es oft weniger um Fakten als um emotional aufgeladene Meinungen geht. Dass dies so ist, liegt auch daran, dass sich Wissenschaftlerinnen und Wissenschaftler bei dem Thema oft zurückhaltend oder gar nicht äußern.

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21.04.2024

Myosin II actively regulates Drosophila proprioceptors

Authors Guan C, Nishi K, Kreis CT, Baeumchen O, Goepfert MC, Schmidt CF Journal BioRxiv Citation bioRxiv 2024.04.18.590050. Abstract Auditory receptors can be motile to actively amplify their mechanical input. Here we describe a novel and different type of motility that, residing in supporting cells, shapes physiological responses of mechanoreceptor

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18.04.2024

Microtubules: highway to … arrhythmia?

Authors Liutkute A, Prosser BL, Voigt N Journal Cardiovascular Research Citation Cardiovasc Res. 2024 Apr 18:cvae072. Abstract No abstract available DOI 10.1093/cvr/cvae072 Pubmed Link

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18.04.2024

Cerebellar Ex Vivo Magnetic Resonance Imaging at its Feasibility Limit: Up to 77-Microns Isotropic Resolution using Low-Bandwidth Balanced Steady State Free Precession (LoBa-bSSFP) Sequences and 3T Standard Equipment

Authors Weigel M, Dechent P, Galbusera R, Bahn E, Lu PJ, Kappos L, Brueck W, Stadelmann C, Granziera C Journal BioRxiv Citation bioRxiv 2024.04.18.589707. Abstract Background: Ultra-high-resolution magnetic resonance imaging of the ex vivo brain is increasingly becoming an indispensable tool for studying the morphology and potential pathology of the

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16.04.2024

Gerd Hasenfuß erhielt Leopold-Lichtwitz-Medaille

Professor Dr. med. Gerd Hasenfuß erhielt die Leopold-Lichtwitz-Medaille der Deutschen Gesellschaft für Innere Medizin (DGIM) auf dem Jahreskongress in Anerkennung seiner großen Verdienste um die Innere Medizin. Hasenfuß ist seit 1998 Direktor der Klinik für Kardiologie und Pneumologie, Universitätsprofessor für Innere Medizin an der Universitätsmedizin Göttingen und Mitglied im MBExC.

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15.04.2024

Click Chemistry with Cell-Permeable Fluorophores Expands the Choice of Bioorthogonal Markers for Two-Color Live-Cell STED Nanoscopy

Authors Gregor C, Grimm F, Rehman J, Wurm CA, Egner A Journal Cells Citation Cells 2024, 13(8), 683. Abstract STED nanoscopy allows for the direct observation of dynamic processes in living cells and tissues with diffraction-unlimited resolution. Although fluorescent proteins can be used for STED imaging, these labels are often

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13.04.2024

α-Synuclein triggers cofilin pathology and dendritic spine impairment via a PrPC-CCR5 dependent pathway

Authors Oliveira da Silva MI, Santejo M, Babcock IW, Magalhães A, Minamide LS, Won SJ, Castillo E, Gerhardt E, Fahlbusch C, Swanson RA, Outeiro TF, Taipa R, Ruff M, Bamburg JR, Liz MA Journal Cell Death & Disease Citation Cell Death Dis. 2024 Apr 13;15(4):264. Abstract Cognitive dysfunction and dementia

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10.04.2024

A subgroup of light-driven sodium pumps with an additional Schiff base counterion

Authors Podoliak E, Lamm GHU, Marin E, Schellbach AV, Fedotov DA, Stetsenko A, Asido M, Maliar N, Bourenkov G, Balandin T, Baeken C, Astashkin R, Schneider TR, Bateman A, Wachtveitl J, Schapiro I, Busskamp V, Guskov A, Gordeliy V, Alekseev A, Kovalev K Journal Nature Communications Citation Nat Commun. 2024

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10.04.2024

How Natural Enzymes and Synthetic Ribozymes Generate Methylated Nucleotides in RNA

Authors Höbartner C, Bohnsack KE, Bohnsack MT Journal Annual Review of Biochemistry Citation Annu Rev Biochem. 2024 Apr 10. Abstract Methylation of RNA nucleotides represents an important layer of gene expression regulation, and perturbation of the RNA methylome is associated with pathophysiology. In cells, RNA methylations are installed by RNA

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10.04.2024

A novel subgroup of light-driven sodium pumps with an additional Schiff base counterion

Authors Podoliak E, Lamm GHU, Marin E, Schellbach AV, Fedotov DA, Stetsenko A, Asido M, Maliar N, Bourenkov G, Balandin T, Baeken C, Astashkin R, Schneider TR, Bateman A, Wachtveitl J, Schapiro I, Busskamp V, Guskov A, Gordeliy V, Alekseev A, Kovalev K Journal Nature Communications Citation Nat Commun. 2024

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