2023

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27.01.2023

Cholesterol-Induced Nanoscale Variations in the Thickness of Phospholipid Membranes

Authors Chen T, Ghosh A, Enderlein J Journal Nano Letters Citation Nano Lett. 2023 Jan 27. Abstract Graphene-induced energy transfer (GIET) is a recently developed fluorescence-spectroscopic technique that achieves subnanometric optical localization of fluorophores along the optical axis of a microscope. GIET is based on the near-field energy transfer from
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23.01.2023

Towards Unbiased Fluorophore Counting in Superresolution Fluorescence Microscopy

Authors Laitenberger O, Aspelmeier T, Staudt T, Geisler C, Munk A, Egner A Journal Nanomaterials Citation Nanomaterials 2023, 13(3), 459. Abstract With the advent of fluorescence superresolution microscopy, nano-sized structures can be imaged with a previously unprecedented accuracy. Therefore, it is rapidly gaining importance as an analytical tool in the
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Künstlerische Darstellung, die zeigt, wie ein Bild mit der neu entwickelten Methode erzeugt wird. Die fluoreszierenden Atome in der Probe (links) emittieren aufgrund der Röntgenanregung zwei Farben, Grün und Magenta. Das graue runde Objekt stellt eine Optik dar, die einen Schatten auf den Detektor wirft. Der Algorithmus erzeugt dann ein tatsächliches Bild mit zwei Farben, deren Intensität die Dichte der fluoreszierenden Atome in der Probe darstellt. Foto: Markus Osterhoff

23.01.2023

Farbbilder aus dem Schattenwurf

Ein Forschungsteam der Universität Göttingen hat ein neues Verfahren für Röntgenfarbaufnahmen entwickelt. Um nicht nur die chemischen Elemente einer Probe durch Röntgenfluoreszenzanalyse zu bestimmen, sondern auch deren räumliche Verteilung, muss bislang die genutzte Röntgenstrahlung fokussiert und die Probe aufwendig abgerastert werden. Die Wissenschaftlerinnen und Wissenschaftler rund um MBExC Mitglied Tim
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23.01.2023

Patient perspectives on the need for improved hearing rehabilitation: A qualitative survey study of German cochlear implant users

Authors Hunniford V, Kühler R, Wolf B, Keppeler D, Strenzke N, Moser T Journal Frontiers in Neuroscience Citation Front. Neurosci. 17:1105562. Abstract Background The electrical cochlear implant (eCI) partially restores hearing in individuals affected by profound hearing impairment (HI) or deafness. However, the limited resolution of sound frequency coding with
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21.01.2023

Single-cell transcriptomics reveal extracellular vesicles secretion with a cardiomyocyte proteostasis signature during pathological remodeling

Authors Schoger E, Bleckwedel F, Germena G, Rocha C, Tucholla P, Sobitov I, Möbius W, Sitte M, Lenz C, Samak M, Hinkel R, Varga ZV, Giricz Z, Salinas G, Gross JC, Zelarayán LC Journal Communications Biology Citation Commun Biol. 2023 Jan 21;6(1):79. Abstract Aberrant Wnt activation has been reported in failing
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21.01.2023

Simulation of Complex Biomolecular Systems: The Ribosome Challenge

Authors Bock LV, Gabrielli S, Kolá MH, Grubmüller H   Journal Annual Review of Biophysics   Citation Annu. Rev. Biophys. 2023. 52:15.1–15.30.   Abstract Large biomolecular systems are at the heart of many essential cellular processes. The dynamics and energetics of an increasing number of these systems are being studied
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19.01.2023

Graded optogenetic activation of the auditory pathway for hearing restoration

Authors Mittring A, Moser T, Huet AT Journal Brain Stimulation Citation Brain Stimul. 2023 Jan 23:S1935-861X(23)01673-X. Abstract Optogenetic control of neural activity enables innovative approaches to improve functional restoration of diseased sensory and motor systems. For clinical translation to succeed, optogenetic stimulation needs to closely match the coding properties of
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18.01.2023

Impact of the Euro 2020 championship on the spread of COVID-19

Authors Dehning J, Mohr SB, Contreras S, Dönges P, Iftekhar EN, Schulz O, Bechtle P, Priesemann V Journal Nature Communications Citation Nat Commun 14, 122 (2023). Abstract Large-scale events like the UEFA Euro 2020 football (soccer) championship offer a unique opportunity to quantify the impact of gatherings on the spread
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15.01.2023

Uncovering the molecular link between lead toxicity and Parkinson’s disease

Authors Shvachiy L, Geraldes V, Outeiro TF Journal Antioxidants & Redox Signaling Citation Antioxidants & Redox Signaling. 2023. Abstract Parkinson’s disease (PD) is a progressive neurodegenerative disorder that affects millions around the world. The etiology of PD remains unknown, but environmental and ocuppational exposures to heavy metals are likely at
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Auszeichnung in Brüssel: links Dr. Gilles Mordant, rechts Prof. Dr. Didier Viviers, Sekretär der belgischen Königlichen Akademie der Wissenschaften. Foto: privat

10.01.2023

Gilles Mordant awarded annual prize

Mathematician and data scientist Dr. Gilles Mordant from the Institute for Mathematical Stochastics at the University of Göttingen, headed by MBExC-member Prof. Dr. Axel Munk, has received the prize for the Annual Contest (section mathematics) of the Royal Academy of Science, Letters and Fine Arts of Belgium. The prize is
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