2022

09.11.2022

Generation of bright autobioluminescent bacteria by chromosomal integration of the improved lux operon ilux2

Authors Gregor C Journal Scientific Reports Citation Sci Rep. 2022 Nov 9;12(1):19039. Abstract The bacterial bioluminescence system enables the generation of light by living cells without the requirement of an external luciferin. Due to the relatively low light emission, many applications of bioluminescence imaging would benefit from an increase in

Learn More

07.11.2022

Neues GRK zu Herz- & Gehirnerkrankungen an der UMG

Die Deutsche Forschungsgemeinschaft (DFG) fördert von April 2023 für fünf Jahre und mit ca. 6 Millionen Euro ein neues Graduiertenkolleg „Herz und Gehirn: Integrative Forschung über Organgrenzen hinweg“ (GRK 2824) an der Universitätsmedizin Göttingen (UMG) mit integrativen, organübergreifenden Forschungsprojekten und klinischen Studien zu Herz- und Gehirnerkrankungen. „Herz & Gehirn: Integrative

Learn More

07.11.2022

Kantorovich–Rubinstein Distance and Barycenter for Finitely Supported Measures: Foundations and Algorithms

Authors Heinemann F, Klatt M, Munk A Journal Applied Mathematics & Optimization Citation Appl Math Optim 87, 4 (2023). Abstract The purpose of this paper is to provide a systematic discussion of a generalized barycenter based on a variant of unbalanced optimal transport (UOT) that defines a distance between general

Learn More

31.10.2022

Peptide Conjugated Dihydroazulene/Vinylheptafulvene Photoswitches in Aqueous Environment

Authors Corbet BP, Schlüter JM, Cotroneo ER, Crespi S, Simeth NA Journal European Journal of Organic Chemistry Citation Eur. J. Org. Chem. 2022, e202201140 Abstract Light-responsive molecules have seen a major advance in modulating biological functions in recent years. Especially photoswitches are highly attractive building blocks due to the reversible

Learn More

27.10.2022

Human mtRF1 terminates COX1 translation and its ablation induces mitochondrial ribosome-associated quality control

Authors Nadler F, Lavdovskaia E, Krempler A, Cruz-Zaragoza LD, Dennerlein S, Richter-Dennerlein R Journal Nature Communications Citation Nat Commun. 2022 Oct 27;13(1):6406. Abstract Translation termination requires release factors that read a STOP codon in the decoding center and subsequently facilitate the hydrolysis of the nascent peptide chain from the peptidyl

Learn More

25.10.2022

Auszeichnung für interdisziplinäre Forschung

Die Arthur Burkhard-Stiftung für Wissenschaftsförderung verleiht den gleichnamigen Preis im Jahr 2022 an MBExC Mitglied Viola Priesemann vom Max-Planck-Institut für Dynamik und Selbstorganisation (MPI-DS) und der Universität Göttingen. Die mit 10.000 Euro dotierte Auszeichnung wird jährlich an herausragende Wissenschaftler*innen verliehen, die sich in der interdisziplinären Forschung verdient gemacht haben. Link

Learn More

25.10.2022

Cochlear Hair Cell Innervation is Dependent on a Modulatory Function of Semaphorin-3A

Authors Cantu-Guerra HL, Papazian MR, Gorsky AL, Alekos NS, Caccavano A, Karagulyan N, Neef J, Vicini S, Moser T, Coate TM Journal Developmental Dynamics Citation Dev Dyn. 2022 Oct 25. Abstract Background: Proper connectivity between type I spiral ganglion neurons (SGNs) and inner hair cells (IHCs) in the cochlea is

Learn More

22.10.2022

Lost in promiscuity? An evolutionary and biochemical evaluation of HSD10 function in cardiolipin metabolism

Authors Wohlfarter Y, Eidelpes R, Yu RD, Sailer S, Koch J, Karall D, Scholl-Bürgi S, Amberger A, Hillen HS, Zschocke J, Keller MA Journal Cellular and Molecular Life Sciences Citation Cell Mol Life Sci. 2022 Oct 22;79(11):562. Abstract Multifunctional proteins are challenging as it can be difficult to confirm pathomechanisms

Learn More

21.10.2022

Mammalian oocytes store mRNAs in a mitochondria-associated membraneless compartment

Authors Cheng S, Altmeppen G, So C, Welp LM, Penir S, Ruhwedel T, Menelaou K, Harasimov K, Stützer A, Blayney M, Elder K, Möbius W, Urlaub H, Schuh M Journal Science Citation Oct 21;378(6617):eabq4835. Abstract Full-grown oocytes are transcriptionally silent and must stably maintain the messenger RNAs (mRNAs) needed for

Learn More

18.10.2022

Deep, deep learning with BART

Authors Blumenthal M, Luo G, Schilling M, Holme HCM, Uecker M Journal Magnetic Resonance in Medicine Citation Magn Reson Med. 2022 Oct 18. Abstract Purpose: To develop a deep-learning-based image reconstruction framework for reproducible research in MRI. Methods: The BART toolbox offers a rich set of implementations of calibration and reconstruction algorithms for

Learn More

Open Positions