2022

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15.06.2022

Extracellular alpha-synuclein: Sensors, receptors, and responses

Authors Domingues R, Sant’Anna R, da Fonseca ACC, Robbs BK, Foguel D, Outeiro TF Journal Neurobiology of Disease Citation Neurobiol Dis. 2022 Jun 15;168:105696. Abstract Synucleinopathies are a group of progressive neurodegenerative diseases known for the accumulation of insoluble aggregates containing the protein alpha-synuclein (aSyn). Recently, it has been assumed
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Prof. Dr. Patrick Cramer © Irene Böttcher-Gajewski / Max Planck Institute for Multidisciplinary Sciences

14.06.2022

Patrick Cramer in die Berlin-Brandenburgische Akademie der Wissenschaften gewählt

Die Berlin-Brandenburgische Akademie der Wissenschaften (BBAW) zählt mit ihrer über 300-jährigen Geschichte zu den traditionsreichsten wissenschaftlichen Vereinigungen Europas. Patrick Cramer, Direktor am Göttinger Max-Planck-Institut (MPI) für Multidisziplinäre Naturwissenschaften, ist nun eines von 13 neu aufgenommenen Mitgliedern. Link zur Pressemitteilung des MPI-NAT
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10.06.2022

Isotropic Three-Dimensional Dual-Color Super-Resolution Microscopy with Metal-Induced Energy Transfer

Authors Thiele JC, Jungblut M, Helmerich DA, Tsukanov R, Chizhik A, Chizhik AI, Schnermann MJ, Sauer M, Nevskyi O, Enderlein J Journal Science Advances Citation Sci Adv. 2022 Jun 10;8(23):eabo2506. Abstract Over the past two decades, super-resolution microscopy has seen a tremendous development in speed and resolution, but for most
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08.06.2022

Retinal Encoding of Natural Scenes

Authors Karamanlis D, Schreyer HM, Gollisch T Journal Annual Review of Vision Science Citation Annu Rev Vis Sci. 2022 Jun 8. Abstract An ultimate goal in retina science is to understand how the neural circuit of the retina processes natural visual scenes. Yet most studies in laboratories have long been
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Prof. Dr. Helmut Grubmüller © Irene Böttcher-Gajewski / Max-Planck-Institut für Multidisziplinäre Naturwissenschaften

07.06.2022

Helmut Grubmüller in die Leopoldina aufgenommen

Die Nationale Akademie der Wissenschaften Leopoldina hat Helmut Grubmüller, MBExC Mitglied und Direktor am Max-Planck-Institut (MPI) für Multidisziplinäre Naturwissenschaften in Göttingen, als neues Mitglied berufen. Sie würdigt damit seine herausragende wissenschaftliche Leistungen und besondere Expertise auf seinem Fachgebiet. Link zur Pressemitteilung des MPI-NAT
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07.06.2022

Progressive frontal intraosseous lipoma: Detection of the mosaic AKT1 variant discloses Proteus syndrome

Authors Schmidt J, Bremmer F, Brockmann K, Kaulfuß S, Wollnik B Journal Clinical Genetics Citation Clin Genet. 2022 Jun 7. Abstract Proteus syndrome is a very rare disorder with progressive, asymmetrical, and disproportionate overgrowth of body parts with a highly variable phenotype. It is associated with mosaicism for the recurrent
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06.06.2022

Regulated targeting of the monotopic hairpin membrane protein Erg1 requires the GET pathway

Authors Farkas Á, Urlaub H, Bohnsack KE, Schwappach B Journal Journal of Cell Biology Citation J Cell Biol. 2022 Jun 6;221(6):e202201036. Abstract The guided entry of tail-anchored proteins (GET) pathway targets C-terminally anchored transmembrane proteins and protects cells from lipotoxicity. Here, we reveal perturbed ergosterol production in ∆get3 cells and
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03.06.2022

Synaptic transmission at the vestibular hair cells of amniotes

Authors Mukhopadhyay M, Pangrsic T Journal Molecular and Cellular Neuroscience Citation Mol Cell Neurosci. 2022 Jun 3;121:103749. Abstract A harmonized interplay between the central nervous system and the five peripheral end organs is how the vestibular system helps organisms feel a sense of balance and motion in three-dimensional space. The
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02.06.2022

Measuring photophysical transition rates with fluorescence correlation spectroscopy and antibunching

Authors Sakhapov D, Gregor I, Karedla N, Enderlein J Journal Journal of Physical Chemistry Letters Citation J Phys Chem Lett. 2022 Jun 2;13(21):4823-4830. Abstract We present a new method that combines fluorescence correlation spectroscopy (FCS) on the microsecond time scale with fluorescence antibunching measurements on the nanosecond time scale for
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02.06.2022

The relevance of synuclein autoantibodies as a biomarker for Parkinson’s disease

Authors Garg P, Maass F, Sundaram SM, Mollenhauer B, Mahajani S, van Riesen C, Kügler S, Bähr M Journal Molecular and Cellular Neuroscience Citation Mol Cell Neurosci. 2022 Jun 2:103746. Abstract Several studies have investigated if the levels of α-synuclein autoantibodies (α-syn AAb) differ in serum of Parkinson’s disease (PD)
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