Willig, Katrin

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23.02.2022

Environmental enrichment enhances patterning and remodeling of synaptic nanoarchitecture as revealed by STED nanoscopy

Authors Wegner W, Steffens H, Gregor C, Wolf F, Willig KI Journal Elife Citation eLife 2022;11:e73603. Abstract Synaptic plasticity underlies long-lasting structural and functional changes to brain circuitry and its experience-dependent remodeling can be fundamentally enhanced by environmental enrichment. It is however unknown, whether and how the environmental enrichment alters
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09.06.2021

Stable but not rigid: Chronic in vivo STED nanoscopy reveals extensive remodeling of spines, indicating multiple drivers of plasticity

Authors Steffens H, Mott AC, Li S, Wegner W, Švehla P, Kan VWY, Wolf F, Liebscher S, Willig KI Journal Science Advances Citation Sci. Adv. 2021; 7 : eabf2806. Abstract Excitatory synapses on dendritic spines of pyramidal neurons are considered a central memory locus. To foster both continuous adaption and
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01.06.2021

Multi-label in vivo STED microscopy by parallelized switching of reversibly switchable fluorescent proteins

Authors Willig KI, Wegner W, Müller A, Calvet-Fournier V, Steffens H Journal Cell Reports Citation Cell Reports. 2021 Jun 1; 35 (9) 109192. Abstract Despite the tremendous success of super-resolution microscopy, multi-color in vivo applications are still rare. Here we present live-cell multi-label STED microscopy in vivo and in vitro
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