Voigt, Niels

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14.05.2023

The role of structural vs cellular remodeling in arrhythmogenesis: personalized computer models of atrial fibrillation

Authors Pikunov AV, Syunyaev RA, Ali R, Prakosa A, Boyle PM, Steckmeister V, Kutschka I, Rytkin E, Voigt N, Trayanova N, Efimov IR Journal BioRxiv Citation bioRxiv 2023.05.13.540632. Abstract Atrial fibrillation (AF) is a progressive disease involving both structural and functional remodeling. To investigate the contribution of cell-scale functional remodeling
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05.04.2023

Electrophysiological and calcium-handling development during long-term culture of human-induced pluripotent stem cell-derived cardiomyocytes

Authors Seibertz F, Sutanto H, Dülk R, Pronto JRD, Springer R, Rapedius M, Liutkute A, Ritter M, Jung P, Stelzer L, Hüsgen LM, Klopp M, Rubio T, Fakuade FE, Mason FE, Hartmann N, Pabel S, Streckfuss-Bömeke K, Cyganek L, Sossalla S, Heijman J, Voigt N Journal Basic Research in Cardiology
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22.02.2023

Phosphodiesterase 8 governs cAMP/PKA-dependent reduction of L-type calcium current in human atrial fibrillation: a novel arrhythmogenic mechanism

Authors Grammatika Pavlidou N, Dobrev S, Beneke K, Reinhardt F, Pecha S, Jacquet E, Abu-Taha IH, Schmidt C, Voigt N, Kamler M, Schnabel RB, Baczkó I, Garnier A, Reichenspurner H, Nikolaev VO, Dobrev D, Molina CE Journal European Heart Journal Citation Eur Heart J. 2023 Feb 22:ehad086. Abstract Aims: Atrial
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06.12.2022

Targeting Mitochondrial Calcium Handling to Treat Atrial Fibrillation

Authors Voigt N, Maack C, Pronto JRD Journal Journal of the American College of Cardiology Citation J Am Coll Cardiol. 2022 Dec, 80 (23) 2220–2223. Abstract No abstract available DOI 10.1016/j.jacc.2022.09.043 Pubmed Link
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15.09.2022

A modern automated patch-clamp approach for high throughput electrophysiology recordings in native cardiomyocytes

Authors Seibertz F, Rapedius M, Fakuade FE, Tomsits P, Liutkute A, Cyganek L, Becker N, Majumder R, Clauß S, Fertig N, Voigt N. Journal Communications Biology Citation Commun Biol 2022 Sep 15;5(1):969. Abstract Crucial conventional patch-clamp approaches to investigate cellular electrophysiology suffer from low-throughput and require considerable experimenter expertise. Automated
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22.08.2022

There is no F in APC: Using physiological fluoride-free solutions for high throughput automated patch clamp experiments

Authors Rapedius M, Obergrussberger A, Humphries ESA, Scholz S, Rinke-Weiss I, Goetze TA, Brinkwirth N, Rotordam MG, Strassmaier T, Randolph A, Friis S, Liutkute A, Seibertz F, Voigt N, Fertig N Journal Frontiers in Molecular Neuroscience Citation Front. Mol. Neurosci., 22 August 2022. Abstract Fluoride has been used in the
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22.06.2022

Adventures and Advances in Time Travel With Induced Pluripotent Stem Cells and Automated Patch Clamp

Authors Rosholm KR, Badone B, Karatsiompani S, Nagy D, Seibertz F, Voigt N, Bell DC Journal Frontiers in Molecular Neuroscience Citation Front Mol Neurosci. 2022 Jun 22;15:898717. Abstract In the Hollywood blockbuster “The Curious Case of Benjamin Button” a fantastical fable unfolds of a man’s life that travels through time
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22.06.2022

Not the classical serendipity: does doxapram treat atrial fibrillation?

Authors Liutkute, A, Brundel BJ, Voigt, N Journal Cardiovascular Research Citation Cardiovasc Res. 2022 Jun 22;118(7):1613-1614. Abstract No abstract available DOI 10.1093/cvr/cvac044   Pubmed Link  
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02.05.2022

Cellular and mitochondrial mechanisms of atrial fibrillation

Authors Jung P, Seibertz F, Fakuade FE, Ignatyeva N, Sampathkumar S, Ritter M, Li H, Mason FE, Ebert A, Voigt N. Journal Basic Research in Cardiology Citation Basic Res Cardiol. 2022 May 2;117(1):5. Abstract Dilated cardiomyopathy (DCM) is a major risk factor for heart failure and is associated with the
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21.04.2022

Background calcium influx in arrhythmia: lead actor or extra?

Authors Fakuade FE, Fauconnier J, Voigt N. Journal Journal of Physiology Citation J Physiol. 2022 Apr 21. Abstract No abstract available DOI 10.1113/JP283032 Pubmed Link  
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