Voigt, Niels

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12.01.2026

Chamber-specific chromatin architecture guides functional interpretation of disease-associated Cis-regulatory elements in human cardiomyocytes

Authors Haydar S, Bednarz R, Laurette P, Sobitov I, Díaz I Pedrosa N, Videm P, Lueneburg T, Kuß S, Lahm H, Dreßen M, Krane M, Schmidt C, Grüning BA, Voigt N, Streckfuss-Bömeke K, Gilsbach R Journal Nature Communications Citation Nat Commun. 2026 Jan 12;17(1):117. Abstract Cis-regulatory elements (CREs) are noncoding
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15.12.2025

Transforming Atrial Fibrillation Management by Targeting Comorbidities and Reducing Atrial Fibrillation Burden: the 10th AFNET/EHRA Consensus Conference

Authors Svennberg E, Merino JL, Andrade J, Anselmino M, Arbelo E, Boersma E, Boriani G, Breithardt G, Chung M, Chyou J, Cohen A, Nielsen JC, Dichtl W, Diederichsen SZ, Dobrev D, Doehner W, Dworatzek E, Fabritz L, Filgueiras-Rama D, Gimpelewitz C, Hack G, Hatem S, Healey J, Heidbuchel H, Hijazi
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18.11.2025

Analysing complex excitation patterns in cardiac tissue using wave event networks

Authors Von Koeller HF, Schlemmer A, Luther S, Döring Y, Voigt N, Parlitz U   Journal Frontiers in Network Physiology   Citation Front Netw Physiol. 2025 Nov 18;5:1674919.   Abstract Cardiac dynamics is governed by complex electrical wave patterns, with disruptions leading to pathological conditions like atrial or ventricular fibrillation.
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16.10.2025

Nanoscale architecture and dynamics of CaV1.3 channel clusters in cardiac myocytes revealed by single channel nanoscopy

Authors Schwenzer N, Tsukanov R, Kohl T, Basak S, Sobitov I, Seibertz F, Kapoor R, Voigt N, Enderlein J, Lehnart SE   Journal Journal of Molecular and Cellular Cardiology Plus   Citation J Mol Cell Cardiol Plus. 2025 Oct 16;14:100490.   Abstract The clustering of L-type calcium channels (LTCC) for
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15.10.2025

Impaired Atrial Mitochondrial Calcium Handling in Patients With Atrial Fibrillation

Authors Pronto JRD, Mason FE, Rog-Zielinska EA, Fakuade FE, Bülow D, Tóth M, Machwart K, Brandes P, Wiedmann F, Kohlhaas M, Nickel A, Wolf M, Mustroph J, Vu KC, Brandenburg S, Do TQ, Siedler PJ, Ritzenhoff K, Xue Z, Zhou X, Kestel S, Dschun O, Kyshynska O, Kensah G, Rebbeck
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13.10.2025

Peroxisome protein import deficiency causes heart failure in mouse and human

Authors Hofhuis J, Tiburcy M, Hartmann Y, Bersch K, Wagdi A, Gutiérrez-Gutiérrez O, Solano R, Thiele L, Walper M, Göbel M, Hübner W, Berecic B, Casini M, Tirilomis P, Unger A, Lipstein N, Sossalla S, Huser T, Streckfuss-Bömeke K, Elkenani M, Toischer K, Kohlhaas M, Dudek J, Zimmermann WH, Voigt
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19.09.2025

High throughput automated patch-clamp of cardiac ion channels using physiological fluoride-free internal solution

Authors Rapedius M, Obergrussberger A, Scholz S, Rinke-Weiss I, Goetze TA, Brinkwirth N, Rotordam MG, Strassmaier T, Randolph A, Friis S, Yang K, Rathje J, Liutkute A, Seibertz F, Voigt N, Fertig N, Stoelzle-Feix S Journal Journal of Pharmacological and Toxicological Methods Citation J Pharmacol Toxicol Methods. 2025. 135, 107825.
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09.09.2025

Cytosolic calcium handling signature: integration with clinical predictors enhances prediction of postoperative atrial fibrillation

Authors Fakuade FE, Gronwald J, Brandes P, Döring Y, Rubio T, Seibertz F, Knierim M, Abu-Taha IH, El-Essawi A, Jebran AF, Danner BC, Baraki H, Kamler M, Kutschka I, Heijman J, Dobrev D, Schmidt C, Kallenberger SM, Voigt N Journal European Heart Journal Citation Eur Heart J. 2025 Sep 9:ehaf609.
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28.08.2025

Role of Structural Versus Cellular Remodeling in Atrial Arrhythmogenesis: Insights From Personalized Digital Twins

Authors Pikunov AV, Syunyaev RA, Ali R, Prakosa A, Gams A, Boyle PM, Steckmeister V, Kutschka I, Rytkin E, Voigt N, Trayanova N, Efimov IR Journal Circulation: Arrhythmia and Electrophysiology Citation Circ Arrhythm Electrophysiol. 2025 Aug 28:e013898. Abstract Background: Atrial fibrillation (AF) is a progressive disease involving both structural and
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25.08.2025

Blebbistatin reduces calcium buffering in cardiomyocytes: Consequences for cellular electrophysiology

Authors Sobitov I, Ritzenhoff K, Gaulrapp M, Becker L, Liutkute A, Seibertz F, Fakuade FE, Mason FE, Voigt N Journal The Journal of Physiology Citation J Physiol. 2025 Aug 25 Abstract Blebbistatin is an excitation-contraction uncoupling agent commonly used in cardiac optical mapping; however, it has been reported to influence
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