Pape, Constantin

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08.04.2025

Stamped counting for biomedical images

Authors Jeremias J, Pape C Journal Methods in Microscopy Citation Methods in Microscopy, 2025. Abstract Counting objects is an important task in biomedical image analysis, for example to count cells in microscopy or microbial colonies in laboratory applications. Similar to most image analysis tasks, modern approaches to counting rely on
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25.03.2025

Tiling artifacts and trade-offs of feature normalization in the segmentation of large biological images

Authors Buglakova E, Archit A, D’Imprima E, Mahamid J, Pape C, Kreshuk A Journal Arxiv Citation arXiv:2503.19545. Abstract Segmentation of very large images is a common problem in microscopy, medical imaging or remote sensing. The problem is usually addressed by sliding window inference, which can theoretically lead to seamlessly stitched
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12.02.2025

Segment Anything for Microscopy

Authors Archit A, Freckmann L, Nair S, Khalid N, Hilt P, Rajashekar V, Freitag M, Teuber C, Buckley G, von Haaren S, Gupta S, Dengel A, Ahmed S, Pape C Journal Nature Methods Citation Nat Methods. 2025 Feb 12. Abstract Accurate segmentation of objects in microscopy images remains a bottleneck
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16.12.2024

Wrapped up: advancements in volume electron microscopy and application in myelin research

Authors Schadt LC, Ruhwedel T, Pape C, Sasmita AO, Steyer AM, Möbius W Journal Methods in Microscopy Citation Methods in Microscopy. 2024. Abstract The three-dimensional visualization of cellular architecture by volume electron microscopy (vEM) has reignited interest in morphological descriptions of complex tissue. At the same time, the increasing availability
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09.10.2024

One-step nanoscale expansion microscopy reveals individual protein shapes

Authors Shaib AH, Chouaib AA, Chowdhury R, Altendorf J, Mihaylov D, Zhang C, Krah D, Imani V, Spencer RKW, Georgiev SV, Mougios N, Monga M, Reshetniak S, Mimoso T, Chen H, Fatehbasharzad P, Crzan D, Saal KA, Alawieh MM, Alawar N, Eilts J, Kang J, Soleimani A, Müller M, Pape
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05.10.2024

The synaptic vesicle cluster as a controller of pre- and postsynaptic structure and function

Authors Reshetniak S, Bogaciu CA, Bonn S, Brose N, Cooper BH, D’Este E, Fauth M, Fernández-Busnadiego R, Fiosins M, Fischer A, Georgiev SV, Jakobs S, Klumpp S, Köster S, Lange F, Lipstein N, Macarrón-Palacios V, Milovanovic D, Moser T, Müller M, Opazo F, Outeiro TF, Pape C, Priesemann V, Rehling
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17.09.2024

Multiplex Microscopy Assay for Assessment of Therapeutic and Serum Antibodies against Emerging Pathogens

Authors Sartingen N, Stürmer V, Kaltenböck M, Müller TG, Schnitzler P, Kreshuk A, Kräusslich HG, Merle U, Mücksch F, Müller B, Pape C, Laketa V Journal Viruses Citation Viruses 2024, 16(9), 1473. Abstract The emergence of novel pathogens, exemplified recently by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), highlights
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