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10.03.2022

A mathematical model for electrical activity in pig atrial tissue

Authors Peris-Yagüe V, Rubio T, Fakuade FE, Voigt N, Luther S, Majumder R Journal Frontiers in Physiology Citation Front Physiol. 2022 Mar 10;13:812535. Abstract State of the art mathematical models are currently used to bridge the gap between basic research conducted in the laboratory and preclinical research conducted on large
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09.03.2022

Modeling charge separation in charged nanochannels for single-molecule electrometry

Authors Enderlein J, Sakhapov D, Gregor I, Croci M, Karedia N Journal The Journal of Chemical Physics Citation J. Chem. Phys. 156, 105104 (2022) Abstract We model the transport of electrically charged solute molecules by a laminar flow within a nanoslit microfluidic channel with electrostatic surface potential. We derive the governing
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08.03.2022

Simple Model for Encoding Natural Images by Retinal Ganglion Cells with Nonlinear Spatial Integration

Authors Liu JK, Karamanlis D, Gollisch T Journal PLoS Computational Biology Citation PLoS Comput Biol. 2022 Mar 8;18(3):e1009925. Abstract A central goal in sensory neuroscience is to understand the neuronal signal processing involved in the encoding of natural stimuli. A critical step towards this goal is the development of successful
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08.03.2022

A novel single-cell RNA-sequencing approach and its applicability connecting genotype to phenotype in ageing disease

Authors Shomroni O, Sitte M, Schmidt J, Parbin S, Ludewig F, Yigit G, Zelarayan LC, Streckfuss-Bömeke K, Wollnik B, Salinas G Journal Scientific Reports Citation Sci Rep. 2022 Mar 8;12(1):4091. Abstract Single cell multi-omics analysis has the potential to yield a comprehensive understanding of the cellular events that underlie the
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08.03.2022

Colocalization of different neurotransmitter transporters on synaptic vesicles is sparse except for VGLUT1 and ZnT3

Authors Upmanyu N, Jin J, Emde HV, Ganzella M, Bösche L, Malviya VN, Zhuleku E, Politi AZ, Ninov M, Silbern I, Leutenegger M, Urlaub H, Riedel D, Preobraschenski J, Milosevic I, Hell SW, Jahn R, Sambandan S Journal Neuron Citation Neuron. 2022 Mar 4:S0896-6273(22)00146-5. Abstract Vesicular transporters (VTs) define the
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08.03.2022

Doxorubicin induces cardiotoxicity in a pluripotent stem cell model of aggressive B cell lymphoma cancer patients

Authors Haupt LP, Rebs S, Maurer W, Hübscher D, Tiburcy M, Pabel S, Maus A, Köhne S, Tappu R, Haas J, Li Y, Sasse A, Santos CCX, Dressel R, Wojnowski L, Bunt G, Möbius W, Shah AM, Meder B, Wollnik B, Sossalla S, Hasenfuss G, Streckfuss-Bömeke K Journal Basic Research
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08.03.2022

The Synaptic Extracellular Matrix: Long-Lived, Stable, and Still Remarkably Dynamic

Authors Dankovich TM, Rizzoli SO Journal Frontiers in Synaptic Neuroscience Citation Front Synaptic Neurosci. 2022 Mar 8;14:854956. Abstract In the adult brain, synapses are tightly enwrapped by lattices of the extracellular matrix that consist of extremely long-lived molecules. These lattices are deemed to stabilize synapses, restrict the reorganization of their
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07.03.2022

Non-Invasive Optical Motion Tracking Allows Monitoring of Respiratory Dynamics in Dystrophin-Deficient Mice

Authors Svetlove A, Albers J, Hülsmann S, Markus MA, Zschüntzsch J, Alves F, Dullin C Journal Cells Citation Cells. 2022 Mar 7;11(5):918. Abstract Duchenne muscular dystrophy (DMD) is the most common x-chromosomal inherited dystrophinopathy which leads to progressive muscle weakness and a premature death due to cardiorespiratory dysfunction. The mdx
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04.03.2022

White matter integrity in mice requires continuous myelin synthesis at the inner tongue

Authors Meschkat M, Steyer AM, Weil MT, Kusch K, Jahn O, Piepkorn L, Agüi-Gonzalez P, Phan NTN, Ruhwedel T, Sadowski B, Rizzoli SO, Werner HB, Ehrenreich H, Nave KA, Möbius W Journal Nature Communications Citation Nat Commun. 2022 Mar 4;13(1):1163.  Abstract Myelin, the electrically insulating sheath on axons, undergoes dynamic
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02.03.2022

Imaging of arrhythmia: Real-time cardiac magnetic resonance imaging in atrial fibrillation

Authors Laubrock K, von Loesch T, Steinmetz M, Lotz J, Frahm J, Uecker M, Unterberg-Buchwald C Journal European Journal of Radiology Open Citation Eur J Radiol Open. 2022 Mar 2;9:100404. Abstract Objectives: Quantitative evaluations of function, volume and mass are fundamental in the diagnostic workup of different cardiovascular diseases and
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