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Authors Shvachiy L, Amaro-Leal A, Machado F, Rocha I, Geraldes V, Outeiro TF Journal Chemosphere Citation Chemosphere. 2025 May 9;380:144477. Abstract Lead, a toxic heavy metal, is prevalent in various industrial applications, contributing to environmental contamination and significant health concerns. Lead affects various body systems, especially the brain, causing long-lasting

Authors Bögershausen N, Cavdarli B, Nagai TH, Milev MP, Wolff A, Mehranfar M, Schmidt J, Choudhary D, Gutiérrez-Gutiérrez Ó, Cyganek L, Saint-Dic D, Zibat A, Köhrer K, Wollenweber TE, Wieczorek D, Altmüller J, Borodina T, Kaçar D, Haliloğlu G, Li Y, Thiel C, Sacher M, Knapik EW, Yigit G, Wollnik

Authors Haertter D, Hauke L, Driehorst T, Nishi K, Long J, Tiburcy M, Berecic B, Primeßnig A, Bao G, Cyganek L, Schmidt CF, Zimmermann WH Journal BioRxiv Citation bioRxiv 2025.04.29.650605. Abstract Cardiomyocyte function critically depends on sarcomere dynamics and their organization in myofibrils. To uncover how cardiomyocyte function emerges from

Authors Shahidi N, Rozenblit F, Khani MH, Schreyer HM, Mietsch M, Protti DA, Gollisch T Journal PLoS Computational Biology Citation PLoS Comput Biol. 2025 May 2;21(5):e1013031. Abstract The dichotomy of excitation and suppression is one of the canonical mechanisms explaining the complexity of neural activity. Computational models of the interplay

Authors Kovalev K, Stetsenko A, Trunk F, Marin E, Haro-Moreno JM, Lamm GHU, Alekseev A, Rodriguez-Valera F, Schneider TR, Wachtveitl J, Guskov A Journal BioRxiv Citation bioRxiv 2025.04.29.651185. Abstract Rhodopsins are light-sensitive membrane proteins capturing solar energy via a retinal cofactor covalently attached to a lysine residue. Several groups of

Authors Groshkova MB, Alvanos T, Qi Y, Wang F, Wichmann C, Hua Y, Moser T Journal Frontiers in Cellular Neuroscience Citation Front. Cell. Neurosci., 28 April 2025 Abstract Introduction: Synapses vary greatly in synaptic strength and plasticity, even within the same circuitry or set of pre- and postsynaptic neurons. Neuromodulation

Authors Tovtik R, Marzin D, Weigel P, Crespi S, Simeth NA Journal Beilstein Journals of Organic Chemistry Citation Beilstein J Org Chem. 2025 Apr 25;21:830-838. Abstract Phenylazopyrazole photoswitches proved to be valuable structural motifs for various applications ranging from materials science to medicine. Despite their potential, their structural diversity is

Authors Kapoor R, Kim H, Garlick E, Lima MARBF, Ruhwedel T, Moebius W, Wolf F, Moser T Journal BioRxiv Citation bioRxiv 2025.04.22.649963. Abstract For us to hear, the cochlea encodes sounds into neural signals at synapses of inner hair cells (IHCs) and the auditory nerve with remarkable fidelity. To achieve

Authors Preobraschenski J, Kreutzberger AJB, Ganzella M, Münster-Wandowski A, Kreutzberger MAB, Oolsthorn LHM, Seibert S, Kiessling V, Riedel D, Witkowska A, Ahnert-Hilger G, Tamm LK, Jahn R Journal Science Advances Citation Sci Adv. 2025 Apr 25;11(17):eads4661. Abstract Synaptic transmission is mediated by the exocytotic release of neurotransmitters stored in synaptic

Authors Harris SS, Ellingford R, Hartmann J, Dasgupta D, Kehring M, Rajani RM, Graykowski D, Quittot N, Sivasankaran D, Commins C, Fan Z, Bond SA, Wolf F, Dupret D, Dolan RJ, Konnerth A, Neef A, Hyman BT, Busche MA Journal Cell Citation Cell. 2025 Apr 23:S0092-8674(25)00408-8. Abstract Tau accumulation is