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08.08.2025

Update on Gastric Pacemaking: Relevance for Gastroparesis

Authors Riebeling J, Patejdl R, Zipf D, Conradi LC, Ghadimi M, Gundling F, Bruegmann T. Journal Zentralblatt für Chirurgie Citation Zentralbl Chir. 2025 Aug;150(4):337-345. German. Abstract Gastroparesis is a disease in which gastric emptying is significantly decreased in the absence of a mechanical obstruction of the gastric outlet. In addition
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06.08.2025

Microglia-neuron crosstalk via Hex-GM2-MGL2 maintains brain homeostasis

Authors Frosch M, Shimizu T, Wogram E, Amann L, Gruber L, Groisman AI, Fliegauf M, Schwabenland M, Chhatbar C, Zechel S, Rosewich H, Gärtner J, Quintana FJ, Buescher JM, Blank T, Binder H, Stadelmann C, Letzkus JJ, Hopf C, Masuda T, Knobeloch KP, Prinz M Journal Nature Citation Nature. 2025
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02.08.2025

Hierarchically ordered multi-timescale structural dynamics of the intrinsically disordered p53 transactivation domain

Authors Szöllősi D, Pratihar S, Mukhopadhyay D, Rout AK, Reddy GJ, Ebersberger N, Becker S, Nagy G, Rauscher S, Lee D, Klement R, Griesinger C, Grubmüller H Journal BioRxiv Citation bioRxiv 2025.08.01.668138 Abstract Intrinsically disordered proteins (IDPs) exhibit pronounced structural dynamics, which is crucial for their functional versatility. Yet their
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01.08.2025

Local Poisson Deconvolution for Discrete Signals

Authors Hundrieser S, Manole T, Litskevich D, Munk A Journal Arxiv Citation arXiv:2508.00824. Abstract We analyze the statistical problem of recovering an atomic signal, modeled as a discrete uniform distribution μ, from a binned Poisson convolution model. This question is motivated, among others, by super-resolution laser microscopy applications, where precise
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01.08.2025

Hearing restoration by a low-weight power-efficient multichannel optogenetic cochlear implant system

Authors Jablonski L, Harczos T, Wolf B, Hoch G, Khurana L, Dieter A, Roos L, Hessler R, Ayub S, Ruther P, Moser T Journal Journal of Neural Engineering Citation J Neural Eng. 2025 Aug 1;22(4). Abstract Objective. In case of deafness, electrical cochlear implants (eCIs) bypass dysfunctional or lost hair
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01.08.2025

Transport Dependency: Optimal Transport Based Dependency Measures

Authors Nies TG, Staudt T, Munk A Journal The Annals of Applied Probability Citation Ann. Appl. Probab. 35(4): 2292-2362 (August 2025). Abstract Finding meaningful ways to measure the statistical dependency between random variables ξ and ζ is a timeless statistical endeavor. In recent years, several novel concepts, like the distance
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01.08.2025

Convergence of Empirical Optimal Transport in Unbounded Settings

Authors Staudt T, Hundrieser S Journal Bernoulli Citation Bernoulli 31(3): 1929-1954 (August 2025). Abstract In compact settings, the convergence rate of the empirical optimal transport cost to its population value is well understood for a wide class of spaces and cost functions. In unbounded settings, however, hitherto available results require
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28.07.2025

Efficient and sustained optogenetic control of sensory and cardiac systems

Authors Alekseev A, Hunniford V, Zerche M, Jeschke M, El May F, Vavakou A, Siegenthaler D, Hüser MA, Kiehn SM, Garrido-Charles A, Meyer A, Rambousky A, Alvanos T, Witzke I, Rojas-Garcia KD, Draband MD, Cyganek L, Klein E, Ruther P, Huet A, Trenholm S, Macé E, Kusch K, Bruegmann T,
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24.07.2025

Central limit theorems for the eigenvalues of graph Laplacians on data clouds

Authors Lui C, Trillos NG, Li H, Suchan L Journal Arxiv Citation arXiv:2507.18803. Abstract Given i.i.d.\ samples Xn={x1,…,xn} from a distribution supported on a low dimensional manifold M embedded in Eucliden space, we consider the graph Laplacian operator Δn associated to an ε-proximity graph over Xn and study the asymptotic
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22.07.2025

3D multiscale shape analysis of nuclei and in vivo elastic stress sensors allows force inference

Authors Jurado A, Isensee J, Hofemeier A, Krüger LJ, Wittkowski R, Golestanian R, Bittihn P, Betz T Journal Biophysical Journal Citation Biophys J. 2025 Jul 22:S0006-3495(25)00450-3. Abstract The measurement of stresses and forces at the tissue level has proven to be an indispensable tool for the understanding of complex biological
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