Gollisch, Tim

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20.11.2024

Nonlinear receptive fields evoke redundant retinal coding of natural scenes

Authors Karamanlis D, Khani MH, Schreyer HM, Zapp SJ, Mietsch M, Gollisch T Journal Nature Citation Nature. 2024 Nov 20. Abstract The role of the vertebrate retina in early vision is generally described by the efficient coding hypothesis1,2, which predicts that the retina reduces the redundancy inherent in natural scenes3
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03.09.2024

Applying Super-Resolution and Tomography Concepts to Identify Receptive Field Subunits in the Retina

Authors Krüppel S, Khani MH, Schreyer HM, Sridhar S, Ramakrishna V, Zapp SJ, Mietsch M, Karamanlis D, Gollisch T Journal PLoS Computational Biology Citation PLoS Comput Biol. 2024 Sep 3;20(9):e1012370. Abstract Spatially nonlinear stimulus integration by retinal ganglion cells lies at the heart of various computations performed by the retina.
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20.08.2024

Accelerated spike-triggered non-negative matrix factorization reveals coordinated ganglion cell subunit mosaics in the primate retina

Authors Zapp SJ, Khani MH, Schreyer HM, Sridhar S, Ramakrishna V, Krueppel S, Mietsch M, Protti DA, Karamanlis D, Gollisch T Journal eLife Citation eLife13:RP99945. Abstract A standard circuit motif in sensory systems is the pooling of sensory information from an upstream neuronal layer. A downstream neuron thereby collects signals
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10.03.2024

Modeling spatial contrast sensitivity in responses of primate retinal ganglion cells to natural movies

Authors Sridhar S, Vystrčilová M, Khani MH, Karamanlis D, Schreyer HM, Ramakrishna V, Krüppel S, Zapp SJ, Mietsch M, Ecker A, Gollisch T Journal BioRxiv Citation bioRxiv 2024.03.05.583449. Abstract Retinal ganglion cells, the output neurons of the vertebrate retina, often display nonlinear summation of visual signals over their receptive fields.
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09.03.2024

Convolutional neural network models of the primate retina reveal adaptation to natural stimulus statistics

Authors Vystrčilová M, Sridhar S, Burg MF, Gollisch T, Ecker AS Journal BioRxiv Citation bioRxiv 2024.03.06.583740. Abstract The diverse nature of visual environments demands that the retina, the first stage of the visual system, encodes a vast range of stimuli with various statistics. The retina adapts its computations to some
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29.11.2023

Most discriminative stimuli for functional cell type identification

Authors Burg MF, Zenkel T, Vystrčilová M, Oesterle J, Höfling L, Willeke KF, Lause J, Müller S, Fahey PG, Ding Z, Restivo K, Sridhar S, Gollisch T, Berens P, Tolias AS, Euler T, Bethge M, Ecker AS Journal ArXiv Citation arXiv:2401.05342. Abstract Identifying cell types and understanding their functional properties
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16.06.2023

Diversity of Ganglion Cell Responses to Saccade-like Image Shifts in the Primate Retina

Authors Krüppel S, Khani MH, Karamanlis D, Erol YC, Zapp SJ, Mietsch M, Protti DA, Rozenblit F, Gollisch T Journal Journal of Neuroscience Citation J Neurosci. 2023 Jun 16:JN-RM-1561-22. Abstract Saccades are a fundamental part of natural vision. They interrupt fixations of the visual gaze and rapidly shift the image
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16.12.2022

Molecular Mechanisms Mediating the Transfer of Disease-Associated Proteins and Effects on Neuronal Activity

Authors Brás IC, Khani MH, Vasili E, Möbius W, Riedel D, Parfentev I, Gerhardt E, Fahlbusch C, Urlaub H, Zweckstetter M, Gollisch T, Outeiro TF Journal Journal of Parkinson’s Disease Citation J Parkinsons Dis. 2022;12(8):2397-2422. Abstract Background: Various cellular pathways have been implicated in the transfer of disease-related proteins between
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01.12.2022

Filter-based models of suppression in retinal ganglion cells: comparison and generalization across species and stimuli

Authors Shahidi N, Rozenblit F, Khani MH, Schreyer HM, Mietsch M, Protti DA, Gollisch T Journal BioRxiv Citation bioRxiv 2022.12.01.518577. Abstract The dichotomy of excitation and suppression is one of the canonical mechanisms explaining the complexity of the neural activity. Computational models of the interplay of excitation and suppression in
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08.09.2022

Ectosomes and exosomes modulate neuronal spontaneous activity

Authors Brás IC, Khani MH, Riedel D, Parfentev I, Gerhardt E, van Riesen C, Urlaub H, Gollisch T, Outeiro TF Journal Journal of Proteomics Citation J Proteomics. 2022 Sep 8:104721. Abstract Extracellular vesicles (EVs) are important mediators in intercellular communication. However, understanding the biological origin and functional effects of EVs
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