Brose, Nils

Home >> Publications >> Author >> Brose, Nils
Feature image not available
06.01.2026

CDC42-Effector Proteins Regulate Higher Order Structure of Septins Required for CNS Myelin Integrity

Authors Hümmert S, de Faria JP, Jahn O, Bilgin E, Łukasik N, Rao C, Mitkovski M, Benseler F, Brose N, Siems SB, Goebbels S, Möbius W, Ewers H, Relvas JB, Werner HB Journal Glia Citation Glia. 2026 Mar;74(3):e70134. Abstract The regular structure of CNS myelin requires specialized structural proteins, including
Learn More
Feature image not available
22.10.2025

Pathogenic UNC13A variants cause a neurodevelopmental syndrome by impairing synaptic function

Authors Asadollahi R, Ahmad A, Boonsawat P, Shahanoor Hinzen J, Lohse M, Bouazza-Arostegui B, Sun S, Utesch T, Sommer JD, Ilic D, Padmanarayana M, Fischermanns K, Ranjan M, Boll M, Ka C, Piton A, Mattioli F, Isidor B, Õunap K, Reinson K, Wojcik MH, Marshall CR, Mercimek-Andrews S, Matsumoto N,
Learn More
Feature image not available
17.10.2025

Structure and function of otoferlin, a synaptic protein of sensory hair cells essential for hearing

Authors Chen H, Cretu C, Trebilcock A, Evdokimova N, Babai N, Feldmann L, Leidner F, Benseler F, Mutschall S, Esch K, Szabo CZK, Pena V, Pape C, Grubmüller H, Strenzke N, Brose N, Wichmann C, Preobraschenski J, Moser T Journal Sciende Advances Citation Sci Adv. 2025 Oct 17;11(42):eady8532. Abstract Hearing
Learn More
Feature image not available
17.10.2025

Neuroanatomical characterization of the cell adhesion molecule IgSF9b reveals localization to inhibitory and excitatory synapses in the mouse limbic system

Authors Rotondo F, Ali H, Maichle M, Schmeisser MJ, Brose N, Krueger-Burg D Journal Journal of Molecular Medicine Citation J Mol Med (Berl). 2025 Nov;103(11-12):1551-1565. Abstract Immunoglobulin superfamily member 9b (IgSF9b) is a cell adhesion protein that has been linked to the etiology of several neuropsychiatric disorders, most notably schizophrenia
Learn More
Feature image not available
03.09.2025

Adaptor protein complex 2 (AP2) participates in biogenesis and homeostasis of myelin sheaths in the central nervous system

Authors Siems SB, Jung RB, Jahn O, Meschkat M, Michanski S, Lukasik N, Hummert S, Sasmita AO, Mobius W, Benseler F, Brose N, Kramer-Albers EM, Haucke V, Nave KA, Werner HB Journal BioRxiv Citation bioRxiv 2025.09.02.673641. Abstract Myelination of CNS axons requires oligodendrocytes to undergo extensive morphological changes by producing
Learn More
Feature image not available
28.08.2025

SynapseNet: Deep Learning for Automatic Synapse Reconstruction

Authors Muth S, Moschref F, Freckmann L, Mutschall S, Hojas-Garcia-Plaza I, Bahr JN, Petrovic A, Do TT, Schwarze V, Archit A, Weyand K, Michanski S, Maus L, Imig C, Hintze A, Brose N, Wichmann C, Fernandez-Busnadiego R, Moser T, Rizzoli SO, Cooper BH, Pape C Journal Molecular Biology of the
Learn More
Feature image not available
22.05.2025

Endogenous SNAP-tagging of Munc13-1 for monitoring synapse nanoarchitecture

Authors Kowald M, Bachollet SPJT, Benseler F, Steinecker M, Boll M, Kaushik S, Soykan T, Sun S, Birke R, Ilic D, Brose N, Hörnberg H, Lehmann M, Rizzoli SO, Broichhagen J, Lipstein N Journal JACS Au Citation JACS Au 2025. Abstract Synaptic function is governed by highly regulated protein machineries,
Learn More
Feature image not available
22.03.2025

Number and relative abundance of synaptic vesicles in functionally distinct priming states determine synaptic strength and short-term plasticity

Authors Lin KH, Ranjan M, Lipstein N, Brose N, Neher E, Taschenberger H Journal The Journal of Physiology Citation J Physiol. 2025 Mar 22. Abstract Heterogeneity in synaptic strength and short-term plasticity (STP) was characterized in post-hearing rat calyx of Held synapses at near-physiological external [Ca2+] under control conditions and
Learn More
Feature image not available
05.10.2024

The synaptic vesicle cluster as a controller of pre- and postsynaptic structure and function

Authors Reshetniak S, Bogaciu CA, Bonn S, Brose N, Cooper BH, D’Este E, Fauth M, Fernández-Busnadiego R, Fiosins M, Fischer A, Georgiev SV, Jakobs S, Klumpp S, Köster S, Lange F, Lipstein N, Macarrón-Palacios V, Milovanovic D, Moser T, Müller M, Opazo F, Outeiro TF, Pape C, Priesemann V, Rehling
Learn More
Feature image not available
17.09.2024

Functional Neuroligin-2-MDGA1 interactions differentially regulate synaptic GABAARs and cytosolic gephyrin aggregation

Authors Zeppillo T, Ali H, Ravichandran S, Ritter TC, Wenger S, López-Murcia FJ, Gideons E, Signorelli J, Schmeisser MJ, Wiltfang J, Rhee J, Brose N, Taschenberger H, Krueger-Burg D Journal Communications Biology Citation Commun Biol. 2024 Sep 17;7(1):1157. Abstract Neuroligin-2 (Nlgn2) is a key synaptic adhesion protein at virtually all
Learn More
X

Open Positions

EN DE
X
X