14.04.2025
Authors Galbusera R, Weigel M, Bahn E, Schaedelin S, Cagol A, Lu PJ, Barakovic M, Melie-Garcia L, Franz J, Dechent P, Nair G, Kappos L, Brück W, Stadelmann C, Granziera C Journal Brain Pathology Citation Brain Pathol. 2025 Apr 14:e70010. Abstract Remyelination of cortical lesions in people with multiple sclerosis
13.04.2025
Differentiation of Mature Dopaminergic Neurons from Human Induced Pluripotent Stem Cells
Authors Garg P, Bähr M, Kügler S Journal Methods in Molecular Biology (Clifton, N.J.) Citation Methods Mol Biol. 2025;2910:53-68. Abstract Reprogramming of somatic cells like blood cells and fibroblasts to obtain human induced pluripotent stem cells (hiPSCs) has become a state-of-the-art tool to study human diseases. The self-renewable hiPSCs offer
11.04.2025
A role for astrocytic miR-129-5p in frontotemporal dementia
Authors Kaurani L, Pradhan R, Schröder S, Burkhardt S, Schuetz AL, Krüger DM, Pena T, Heutink P, Sananbenesi F, Fischer A Journal Translational Psychiatry Citation Transl Psychiatry. 2025 Apr 11;15(1):142. Abstract Frontotemporal dementia is a debilitating neurodegenerative disorder characterized by frontal and temporal lobe degeneration, resulting in behavioral changes, language
11.04.2025
Distinct transmission sites within a synapse for strengthening and homeostasis
Authors Yang Y, Wong MH, Huang X, Chiu DN, Liu YZ, Prabakaran V, Imran A, Panzeri E, Chen Y, Huguet P, Kunisky A, Ho J, Dong Y, Carter BC, Xu W, Schlüter OM Journal Science Advances Citation Sci Adv. 2025 Apr 11;11(15):eads5750. Abstract At synapses, miniature synaptic transmission forms the
08.04.2025
Stamped counting for biomedical images
Authors Jeremias J, Pape C Journal Methods in Microscopy Citation Methods in Microscopy, 2025. Abstract Counting objects is an important task in biomedical image analysis, for example to count cells in microscopy or microbial colonies in laboratory applications. Similar to most image analysis tasks, modern approaches to counting rely on
08.04.2025
Understanding inherited cardiomyopathies: clinical aspects and genetic determinants
Authors Yigit G, Kaulfuß S, Wollnik B Journal Medizinische Genetik Citation Med Genet. 2025 Apr 8;37(2):103-111. Abstract Cardiomyopathies (CMs) are a clinically heterogeneous group of cardiovascular diseases characterized by structural and functional abnormalities of the heart muscle in the absence of coronary artery disease, hypertension, valve disease, or congenital heart
07.04.2025
Pioneering partnership shaping the future of regenerative cardiac medicine
With the signing of an equity agreement on April 2, 2025, biotech pioneers Repairon GmbH and life science investor Bioventure Management GmbH, both based in Göttingen, have entered into a strategic partnership with the potential to fundamentally change the treatment of heart failure worldwide. Bioventure is investing in Repairon –
07.04.2025
Modulation of protein activity by small RNA base pairing internal to coding sequences
Authors Thongdee N, Alaniz MM, Samatova E, Zhong A, Esnault C, Zhang H, Dale RK, Rodnina MV, Storz G Journal Molecular Cell Citation Mol Cell. 2025 Mar 30:S1097-2765(25)00258-8. Abstract Most characterized interactions between bacterial small RNAs (sRNAs) and their target mRNAs occur near ribosome binding sites, resulting in changes in
04.04.2025
Recent developments in multiple sclerosis neuropathology
Authors Stadelmann C, Franz J, Nessler S Journal Current Opinion in Neurology Citation Curr Opin Neurol. 2025 Apr 4. Abstract Purpose of review: Neuropathological studies in human brain tissue are indispensable for our understanding of disease mechanisms in multiple sclerosis (MS). They inform concepts of lesion evolution, tissue regeneration and
03.04.2025
Nadja Simeth-Crespi appointed as W2 professor of Molecular Labeling Chemistry
Congratulations to MBExC member Nadja Simeth-Crespi on her appointment as W2 Professor of Molecular Labeling Chemistry at the University of Göttingen! Prof. Simeth-Crespi and her team’s research intersects the boundaries of bioorganic and photochemistry, with a focus on the design of smart drugs, biochemical probes and labels, as well




