2025

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21.05.2025

SMIM20 promotes complex IV biogenesis and Ca2+ signaling in mice heart

Authors Boshnakovska A, Pronto JR, Gall T, Aich A, Prochazka J, Nichtova Z, Sedlacek R, Sobitov I, Ainatzi S, Lenz C, Katschinski DM, Urlaub H, Voigt N, Rehling P, Kremer LS Journal Cell Reports Citation Cell Reports, Volume 44, Issue 6, 115723. Abstract Mitochondria are key to cellular energetics, metabolism,
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Prof. Dr. Timo Betz (Photo: UMG/SPförtner)

21.05.2025

Timo Betz and his team receive audience award in science category

MBExC member Prof. Dr. Timo Betz and his team received the audience award in the science category of the startup competition LIFT-OFF 2025 of the University of Göttingen for their project „ArtifiCell“. The group offers solutions for growing and analysing human 3D miniature tissues in order to test and develop
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20.05.2025

3D imaging of the human temporal bone by X-ray phase-contrast tomography

Authors Schaeper JJ, Tafforeau P, Kampshoff CA, Thomas C, Meyer A, Stadelmann C, Liberman MC, Moser T, Salditt T Journal npj Imaging Citation npj Imaging 3, 21 (2025). Abstract Studying the subtle and intricate three-dimensional structure of the human cochlea embedded in the temporal bone requires structure-preserving imaging approaches with
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The team behind the audiovisual art project for ‘Hearing with Light’: composer Ralf Hildenbeutel, Jenny Blum, audiologist at the Department of Otorhinolaryngology at the University Medical Center Göttingen (UMG), Prof. Dr Tobias Moser, Director of the Institute for Auditory Neuroscience at the UMG, and video artist Boris Seewald (from left to right). Photo: umg/frank stefan kimmel

20.05.2025

Audiovisual art project allows ‘hearing with light’ experience

Under the leadership of the University Medical Center Göttingen (UMG), researchers in Göttingen, together with audiologists and artists from the fields of film and music, have translated the sound experience with an optogenetic cochlear implant into images and sound. The music video artistically conveys the restoration of ‘hearing with light’,
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The team behind the audiovisual art project for ‘Hearing with Light’: composer Ralf Hildenbeutel, Jenny Blum, audiologist at the Department of Otorhinolaryngology at the University Medical Center Göttingen (UMG), Prof. Dr Tobias Moser, Director of the Institute for Auditory Neuroscience at the UMG, and video artist Boris Seewald (from left to right). Photo: umg/frank stefan kimmel

20.05.2025

Audiovisual art project allows ‘hearing with light’ experience

Under the leadership of the University Medical Center Göttingen (UMG), researchers in Göttingen, together with audiologists and artists from the fields of film and music, have translated the sound experience with an optogenetic cochlear implant into images and sound. The music video artistically conveys the restoration of ‘hearing with light’,
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16.05.2025

Chronic Vanadium Exposure Promotes Aggregation of Alpha-Synuclein, Tau and Amyloid Beta in Mouse Brain

Authors Folarin OR, Olopade FE, Gilbert TT, Ladagu AD, Pires Dos Santos PI, Mustapha OA, Kpasham LZ, Olopade JO, Outeiro TF Journal Journal of Neurochemistry Citation J Neurochem. 2025 May;169(5):e70082. Abstract The interaction of toxic environmental metals and metalloids with brain proteins and polypeptides can result in pathological aggregations and
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15.05.2025

Combinatorial transcriptional regulation establishes subtype-appropriate synaptic properties in auditory neurons

Authors Bastille I, Lee L, Moncada-Reid C, Yu WM, Sitko A, Yung A, Zamani M, Christophersen N, Maroofian R, Galehdari H, Babai N, Vona B, Moser T, Goodrich L Journal Cell Reports Citation Cell Rep 2025. accepted manuscript. Abstract Neurons develop diverse synapses that vary in content, morphology, and size.
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12.05.2025

Detection and inference of changes in high-dimensional linear regression with non-sparse structures

Authors Cho H, Kley T, Li H Journal Journal of the Royal Statistical Society, Series B Citation J R Stat Soc Series B: Stat Method. 2025. accepted manuscript. Abstract For data segmentation in high-dimensional linear regression settings, the regression parameters are often assumed to be sparse segment-wise, which enables many
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12.05.2025

Brain-derived synaptic vesicles have an intrinsic ability to sequester tubulin

Authors Mimoso T, Korobeinikov A, Stein A, Milovanovic D, Rizzoli SO, Köster S, Reshetniak S Journal BioRxiv Citation bioRxiv 2025.05.08.652815 Abstract The presence and function of microtubules within the synaptic bouton has long been under investigation. In recent years evidence has accumulated that connects the synaptic vesicle cluster to the
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In the cochlea of the inner ear, sound waves are detected in a frequency-specific manner and subsequently transmitted to the brain. Image @ Christian Vogl, Carlos Duque Afonso, Tobias Moser, Institute for Auditory Neuroscience, UMG.

11.05.2025

Illumination in the cochlea

Frankfurter Allgemeine Sonntagszeitung reports on hearing research in Göttingen: A new dimension of hearing for those who are deaf or extremely hard of hearing. A large research network in Göttingen around MBExC member Tobias Moser is developing a high-tech hearing aid that uses light and genetic engineering to enable hearing.
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