December 2025

29.12.2025

Sarcomere analysis in human cardiomyocytes by computing radial frequency spectra

Authors Habeck M, Saleem HN, Plota D, Cheruiyot C, Kohl T, Lehnart SE, Jakobs S, Ebert A Journal Biological Chemistry Citation Biol Chem. 2025 Dec 29. Abstract In cardiomyocytes, the basic contractile unit are sarcomeres, which are organized in a regular manner facilitating their function. Here, we present a new

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27.12.2025

Unlocking microglia pyroptosis in a model of type I interferon-driven neuroinflammation: lessons from Rnaset2-/- mice.

Authors Wendland K, Irsfeld M, Schreiber K, Ternka K, Stadelmann C, Nessler S, Gärtner J, Kettwig M Journal Cell Death & Disease Citation Cell Death Dis. 2025 Dec 27. Abstract RNaseT2-deficient cystic leukoencephalopathy (CLE) presents with severe psychomotor retardation, cystic brain lesions, white matter alterations, and cerebral atrophy. The Rnaset2−/−

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26.12.2025

Uncovering the Complexity of Synucleinopathies: An Ongoing Tale Between Proteins and Lipids

Authors Flores-León M, Outeiro TF Journal Movement Disorders Citation Mov Disord. 2025 Dec 26. Abstract Neurodegenerative diseases are pathological states characterized by progressive alterations in brain homeostasis during aging. Synucleinopathies, including Parkinson’s disease and dementia with Lewy bodies, are defined neuropathologically by the accumulation of inclusions known as Lewy bodies

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23.12.2025

Complement C4d Informs the Differential Diagnosis of Inflammatory Demyelinating CNS Diseases

Authors Landt C, Held F, Kolotourou K, Guranda M, Vakrakou AG, Franz J, Thomas C, Schmiedeknecht MUH, Bergann K, Wrzos C, Endmayr V, Tsaktanis T, Zechel S, Ancău M, Misgeld T, Hakroush S, Hametner S, Rothhammer V, Höftberger R, Hemmer B, Stadelmann C, Nessler S Journal Neurology: Neuroimmunology and Neuroinflammation

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19.12.2025

Faster, clearer, deeper 3D imaging

Research team optimises microscope with innovative technology to benefit research and medicine Light sheet microscopy produces impressive 3D images of tissue and entire organs, such as the delicate cochlea in the inner ear or the complex brain of a mouse. A thin layer of light, the light sheet, moves

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19.12.2025

Faster, clearer, deeper 3D imaging

Research team optimises microscope with innovative technology to benefit research and medicine Light sheet microscopy produces impressive 3D images of tissue and entire organs, such as the delicate cochlea in the inner ear or the complex brain of a mouse. A thin layer of light, the light sheet, moves

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19.12.2025

How coordination emerges during real-time social interaction

New study elucidates continuous dynamics of cooperation and competition When people reach for the same object, walk through a narrow doorway, forage for food, or work together on a shared task, they continuously negotiate—often without noticing—how much to cooperate or compete. Unlike classical laboratory games that force players to

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19.12.2025

How coordination emerges during real-time social interaction

New study elucidates continuous dynamics of cooperation and competition When people reach for the same object, walk through a narrow doorway, forage for food, or work together on a shared task, they continuously negotiate—often without noticing—how much to cooperate or compete. Unlike classical laboratory games that force players to

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19.12.2025

Season’s Greetings

Merry Christmas, season’s greetings, and best wishes for you and your families for a joyful, healthy and successful year 2026!

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17.12.2025

BioimageAIpub: a toolbox for AI-ready bioimaging data publishing

Authors Dvoretskii S, Archit A, Pape C, Moore J, Nolden M Journal Arxiv Citation arXiv:2512.15820. Abstract Modern bioimage analysis approaches are data hungry, making it necessary for researchers to scavenge data beyond those collected within their (bio)imaging facilities. In addition to scale, bioimaging datasets must be accompanied with suitable, high-quality

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