12.06.2025
Authors Gisa V, Islam MR, Lbik D, Hofmann RM, Pena T, Krüger DM, Burkhardt S, Schütz AL, Sananbenesi F, Toischer K, Fischer A Journal Non-coding RNA Citation Noncoding RNA. 2025 Jun 12;11(3):45. Abstract Background: Heart failure (HF) is associated with an increased risk of cognitive impairment and hippocampal dysfunction, yet
11.06.2025
The amyloid precursor family of proteins in excitatory neurons are essential for regulating cortico-hippocampal circuit dynamics in vivo
Authors Harris SS, Rajani RM, Zünkler J, Ellingford R, Yang M, Rowland JM, Schmidt A, Lee BI, Kehring M, Hellmuth M, Lam FKW, Fässler D, Erdinger S, Wolfer DP, Sala Frigerio C, Wolf F, Hyman BT, Müller UC, Busche MA Journal Cell Reports Citation Cell Rep. 2025 Jun 11;44(6):115801. Abstract
10.06.2025
Disease Severity Across Psychiatric Disorders Is Linked to Pro-Inflammatory Cytokines
Authors Solomon P, Budde M, Kohshour MO, Adorja K, Heilbronner M, Navarro-Flores A, Papiol S, Reich-Erkelenz D, Schulte EC, Senner F, Vogl T, Kaurani L, Krüger DM, Sananbenesi F, Pena T, Burkhardt S, Schütz AL, Anghelescu IG, Arolt V, Baune BT, Dannlowski U, Dietrich DE, Fallgatter AJ, Figge C, Juckel
10.06.2025
Dual effect of alpha-synuclein disease variants on condensate formation
Authors Chandran A, Agarwal A, Wang T, Amaral L, Chaves SR, Outeiro TF, Lautenschlager J Journal BioRxiv Citation bioRxiv 2025.06.06.657340. Abstract Alpha-synuclein is a pre-synaptic protein implicated in synucleinopathies like Parkinson’s disease and Dementia with Lewy Bodies, where it accumulates in intracellular aggregates termed Lewy bodies and Lewy neurites. Recent
10.06.2025
Innovative technology provides new insights into the development of serious diseases
Researchers at the University Medical Center Göttingen (UMG) are developing a new method to better understand the energy production of human cells. Disruptions in this process lead to serious and often fatal diseases that can affect skeletal muscle and nerve cells as well as the heart. The results have been
10.06.2025
Innovative technology provides new insights into the development of serious diseases
Researchers at the University Medical Center Göttingen (UMG) are developing a new method to better understand the energy production of human cells. Disruptions in this process lead to serious and often fatal diseases that can affect skeletal muscle and nerve cells as well as the heart. The results have been
04.06.2025
Madame de Staël Prize awarded to Viola Priesemann
The ALLEA award recognizes MBExC member Viola Priesemann, Board Member of the German Young Academy (“Die Junge Akademie”), for her groundbreaking contributions to interdisciplinary science, her exceptional leadership during the pandemic, and her dedication to fostering pan-European collaboration in science, policy, and public health. Link to the press release
03.06.2025
NeuID, a novel neuron-specific lncRNA, resolved a key epigenetic mechanisms linking gene silencing to Alzheimer’s disease
Authors Pradhan R, Petrovic Z, Sakib MS, Schroeder S, Krueger DM, Pena T, Diniz E, Burkhardt S, Schuetz AL, Grządzielewska I, Toischer K, Stein TD, Blusztajn JK, Delalle I, Radulovic J, Sananbenesi F, Fischer A Journal BioRxiv Citation bioRxiv 2025.06.01.657217. Abstract The increasing evidence that non-coding RNAs can become deregulated
03.06.2025
Learning to cluster neuronal function
Authors Nellen NS, Turishcheva P, Vystrčilová M, Sridhar S, Gollisch T, Tolias AS, Ecker AS Journal Arxiv Citation arXiv:2506.03293. Abstract Deep neural networks trained to predict neural activity from visual input and behaviour have shown great potential to serve as digital twins of the visual cortex. Per-neuron embeddings derived from
02.06.2025
Audiovisual art project lets you experience “hearing with light”
Under the leadership of the University Medical Center Göttingen (UMG), researchers from Göttingen, together with audiologists and artists from the fields of film and music, have translated the sound experience with an optogenetic cochlear implant into image and sound. The music video artistically conveys the restoration of “hearing with light”,