January

Home >> 2025 >> January
Feature image not available
31.01.2025

Cryo-ET suggests tubulin chaperones form a subset of microtubule lumenal particles with a role in maintaining neuronal microtubules

Authors Chakraborty S, Martinez-Sanchez A, Beck F, Toro-Nahuelpan M, Hwang IY, Noh KM, Baumeister W, Mahamid J Journal Proceedings of the National Academy of Sciences of the United States of America Citation Proc Natl Acad Sci U S A. 2025 Feb 4;122(5):e2404017121. Abstract The functional architecture of the long-lived neuronal
Learn More
Feature image not available
31.01.2025

An avoidance segment resolves a lethal nuclear-mitochondrial targeting conflict during ribosome assembly

Authors Oborská-Oplová M, Geiger AG, Michel E, Klingauf-Nerurkar P, Dennerlein S, Bykov YS, Amodeo S, Schneider A, Schuldiner M, Rehling P, Panse VG Journal Nature Cell Biology Citation Nat Cell Biol. 2025 Jan 31. Abstract The correct sorting of nascent ribosomal proteins from the cytoplasm to the nucleus or to
Learn More
Feature image not available
30.01.2025

Advanced fluorescence lifetime-enhanced multiplexed nanoscopy of cells

Authors Basak S, Tsukanov R Journal Methods in Microscopy Citation Methods in Microscopy, 2025. Abstract In this review paper, we summarize the significant advancements in the field of fluorescence lifetime imaging microscopy (FLIM), particularly wide-field FLIM with single-molecule sensitivity, achieved using the time-correlated single-photon counting-based position-sensitive LINCam system. Fluorescence lifetime
Learn More
Feature image not available
29.01.2025

Engineered heart muscle allografts for heart repair in primates and humans

Authors Jebran AF, Seidler T, Tiburcy M, Daskalaki M, Kutschka I, Fujita B, Ensminger S, Bremmer F, Moussavi A, Yang H, Qin X, Mißbach S, Drummer C, Baraki H, Boretius S, Hasenauer C, Nette T, Kowallick J, Ritter CO, Lotz J, Didié M, Mietsch M, Meyer T, Kensah G, Krüger
Learn More
Feature image not available
29.01.2025

Cortical population coding critically depends on fine-tuning of cell physiology

Authors Revah O, Wolf F, Gutnick MJ, Neef A Journal Biorxiv Citation bioRxiv 2024.02.15.580451. Abstract Cortical function reflects the activities of populations of neurons. How accurately they can encode information depends on the speed with which each neuron can respond to input, as revealed by dynamic gain analysis. Theory predicts
Learn More

The heart patch is produced from induced pluripotent stem cells derived heart muscle cells in a collagen hydrogel. Illustration: umg/eva meyer-besting

29.01.2025

Study results open door to heart failure treatment with ‘heart patch’

Results from rhesus macaques provide solid ground for a first-in-human investigation of heart repair with stem cell-derived engineered heart muscle. The study is a milestone for the clinical application of the ‘heart patch’ as an innovative treatment option for patients with advanced heart failure at the University Medical Center Göttingen
Learn More

The heart patch is produced from induced pluripotent stem cells derived heart muscle cells in a collagen hydrogel. Illustration: umg/eva meyer-besting

29.01.2025

Study results open door to heart failure treatment with ‘heart patch’

Results from rhesus macaques provide solid ground for a first-in-human investigation of heart repair with stem cell-derived engineered heart muscle. The study is a milestone for the clinical application of the ‘heart patch’ as an innovative treatment option for patients with advanced heart failure at the University Medical Center Göttingen
Learn More
Feature image not available
28.01.2025

Computational functions of precisely balanced neuronal microcircuits in an olfactory memory network

Authors Meissner-Bernard C, Jenkins B, Rupprecht P, Bouldoires EA, Zenke F, Friedrich RW, Frank T Journal Cell Reports Citation Cell Reports 44, 115330, March 25, 2025. Abstract Models of balanced autoassociative memory networks predict that specific inhibition is critical to store information in connectivity. To explore these predictions, we characterized
Learn More
Feature image not available
27.01.2025

Structural Basis of Lipid Membrane Binding by Human Ferlins

Authors Cretu C, Chernev A, Szabo CZK, Pena V, Urlaub H, Moser T, Preobraschenski J Journal BioRxiv Citation bioRxiv 2025.01.25.634844. Abstract Ferlins, ancient membrane proteins with a unique architecture, are central to multiple essential, Ca2+-dependent vesicle fusion processes. Despite numerous functional studies and their link to burdening human diseases, a
Learn More
Feature image not available
25.01.2025

Gating of hair cell Ca2+ channels governs the activity of cochlear neurons

Authors Karagulyan N, Thirumalai A, Michanski S, Qi Y, Fang Q, Wang H, Ortner NJ, Striessnig J, Strenzke N, Wichmann C, Hua Y, Moser T Journal BioRxiv Citation bioRxiv 2025.01.23.634330. Abstract Our sense of hearing processes sound intensities spanning six orders of magnitude. In the ear, postsynaptic spiral ganglion neurons
Learn More
X

Open Positions

EN DE
X
X