05.07.2023
Authors Priesmeier L, Schoger E, Cyganek L, Zelarayán LC Journal Stem Cell Research Citation Stem Cell Res. 2023 Jul 5;71:103163. Abstract Towards increasing the possibility for temporal control of gene expression using CRISPR activation (a) systems, we generated homozygous human induced pluripotent stem cell (hiPSC) lines carrying a doxycycline (dox)-inducible
02.07.2023
AI and protein structure and function in neurological disease: relevance to disease management
Authors Outeiro TF, Vieira TCRG Journal Nature Reviews. Neurology Citation Nat Rev Neurol. 2023 Jul 2. Abstract No abstract available. DOI 10.1038/s41582-023-00840-z Pubmed Link
01.07.2023
Polychaetoid/ZO-1 strengthens cell junctions under tension while localizing differently than core adherens junction proteins
Authors Peifer M, Schmidt A, Finegan T, Häring M, Kong D, Fletcher AG, Alam Z, Grosshans J, Wolf F Journal Molecular Biology of the Cell Citation Mol Biol Cell. 2023 Jul 1;34(8):ar81. Abstract During embryonic development, dramatic cell shape changes and movements reshape the embryonic body plan.
30.06.2023
Multiple sclerosis: Myelin may threaten nerve fiber survival
Multiple sclerosis (MS) affects millions of people worldwide and so far there is no cure for this disease of the central nervous system. Damage to nerve fibers, also called axons, is responsible for the severity of the disease in patients and the course of MS. The protective layer of the
30.06.2023
Cryo-electron tomography of large biological specimens vitrified by plunge freezing
Authors Baeuerlein FJB, Renner M, El Chami D, Lehnart SE, Pastor-Pareja JC, Fernandez-Busnadiego R Journal BioRxiv Citation bioRxiv 2021.04.14.437159. Abstract Cryo-focused ion beam (cryo-FIB) milling allows thinning vitrified cells for high resolution imaging by cryo-electron tomography (cryo-ET). However, it remains challenging to apply this workflow to voluminous biological specimens such
29.06.2023
Translation termination in human mitochondria – substrate specificity of mitochondrial release factors
Authors Nadler F, Richter-Dennerlein R Journal Biological Chemistry Citation Biol Chem. 2023 Jun 29. Abstract Mitochondria are the essential players in eukaryotic ATP production by oxidative phosphorylation, which relies on the maintenance and accurate expression of the mitochondrial genome. Even though the basic principles of translation are conserved due to
29.06.2023
Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease
Authors Schäffner E, Bosch-Queralt M, Edgar JM, Lehning M, Strauß J, Fleischer N, Kungl T, Wieghofer P, Berghoff SA, Reinert T, Krueger M, Morawski M, Möbius W, Barrantes-Freer A, Stieler J, Sun T, Saher G, Schwab MH, Wrede C, Frosch M, Prinz M, Reich DS, Flügel A, Stadelmann C, Fledrich
29.06.2023
State of Lower Saxony supports further preclinical development of optical cochlear implants
The State of Lower Saxony and the VolkswagenFoundation have granted researchers of the University Medical Center Göttingen, the Leibniz University Hannover and the Clusters of Excellence Multiscale Bioimaging and Hearing4all funding by the zukunft.niedersachsen program. Their project on the development of optical cochlear implants for the restoration of hearing in
29.06.2023
State of Lower Saxony supports further preclinical development of optical cochlear implants
The State of Lower Saxony and the VolkswagenFoundation have granted researchers of the University Medical Center Göttingen, the Leibniz University Hannover and the Clusters of Excellence Multiscale Bioimaging and Hearing4all funding by the zukunft.niedersachsen program. Their project on the development of optical cochlear implants for the restoration of hearing in
29.06.2023
Mechanisms of inward transmembrane proton translocation
Authors Kovalev K, Tsybrov F, Alekseev A, Shevchenko V, Soloviov D, Siletsky S, Bourenkov G, Agthe M, Nikolova M, von Stetten D, Astashkin R, Bukhdruker S, Chizhov I, Royant A, Kuzmin A, Gushchin I, Rosselli R, Rodriguez-Valera F, Ilyinskiy N, Rogachev A, Borshchevskiy V, Schneider TR, Bamberg E, Gordeliy V




