2022

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Reconstruction of a mitochondrion based on electron microscopic data (Source: P. Ilgen/Jacobs Lab)

14.10.2022

Focus on Mitochondrial Nanostructure: DFG FOR 2848 “Nanoscale Architecture and Heterogeneity of the Mitochondrial Inner Membrane” funded for another 3 years

The DFG FOR (“Research Unit”) 2848 “Nanoscale Architecture and Heterogeneity of the Mitochondrial Inner Membrane” coordinated by MBExC member Stefan Jakobs (Clinic for Neurology, UMG/MPI for Multidisciplinary Sciences) is funded for another 3 years with 1.3 Million Euros. Since 2019, the scientists have been working on questions concerning the nanostructure
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11.10.2022

Homozygous loss-of-function variants in FILIP1 cause autosomal recessive arthrogryposis multiplex congenita

Authors Schnabel F, Schuler E, Al-Maawali A, Chaurasia A, Syrbe S, Al-Kindi A, Bhavani GS, Shukla A, Altmüller J, Nürnberg P, Banka S, Girisha KM, Li Y, Wollnik B, Yigit G Journal Human Genetics Citation Human Genetics. preprint under review. 2022 Abstract Arthrogryposis multiplex congenita forms a broad group of
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11.10.2022

Editorial: Cardiac optogenetics: Using light to observe and excite the heart

Authors Bruegmann T, Smith GL, Lehnart SE Journal Frontiers in Physiology Citation Front Physiol. 2022 Oct 11;13:1031062. Abstract No abstract available. DOI 10.3389/fphys.2022.1031062   Pubmed Link  
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10.10.2022

In silico modeling for personalized stenting in aortic coarctation

Authors Ma D, Wang Y, Azhar M, Adler A, Steinmetz M, Uecker M Journal Engineering Applications of Computational Fluid Mechanics Citation Engineering Applications of Computational Fluid Mechanics, 16:1, 2056-2073. Abstract Stent intervention is a recommended therapy to reduce the pressure gradient and restore blood flow for patients with coarctation of
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10.10.2022

From LUVs to GUVs – how to cover micrometer-sized pores with membranes

Authors Kramer K, Sari M, Schulze K, Flegel H, Stehr M, Mey I, Janshoff A, Steinem C Journal Journal of Physical Chemistry B Citation J. Phys. Chem. B 2022, 126, 41, 8233–8244. Abstract Pore-spanning membranes (PSMs) are a versatile tool to investigate membrane-confined processes in a bottom-up approach. Pore sizes
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Will Seibertz and Niels Voigt at Nanion SynchroPatch 384, Photo: Swen Pförtner/UMG

10.10.2022

Adult mammalian cardiomyocytes successfully recorded for the first time on a high throughput automated patch clamp instrument

The group of MBExC member Niels Voigt with first author HSC member Will Seibertz and co-authors demonstrate for the first time successful recordings of all expected ion channel currents and action potentials from freshly isolated mammalian atrial and ventricular cardiomyocytes on the Nanion SyncroPatch 384. This work has recently been
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Prof. Dr. Peter Rehling, director of the Institute for Cell Biochemistry, UMG. Photo: MBExC

05.10.2022

European top funding for investigating the exciting mechanisms of mitochondrial gene expression

Prof. Dr. Peter Rehling, cell biochemist at the University Medical Center Göttingen recives for the second time an Advanced Grant of the European Research Council (ERC). (umg/mbexc) Prof. Dr. Peter Rehling, Director of the Institute of Cellular Biochemistry at the University Medical Center Göttingen (UMG), spokesperson of the Göttingen Collaborative
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Prof. Dr. Peter Rehling, director of the Institute for Cell Biochemistry, UMG. Photo: MBExC

05.10.2022

ERC Advanced Grant for Peter Rehling

Prof. Dr. Peter Rehling, Director of the Institute of Cellular Biochemistry at the University Medical Center Göttingen (UMG), spokesperson of the Göttingen Collaborative Research Center 1190 “Compartmental Gates and Contact Sites in Cells” and member of the Cluster of Excellence “Multiscale Bioimaging: From Molecular Machines to Networks of Excitable Cells”
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04.10.2022

Viola Priesemann takes up professorship at the University of Göttingen

On 1st October 2022, physicist and MBExC member Viola Priesemann has taken up a professorship in the field of theroretical physics at the University of Göttingen. Since 2017, she leads the research group “Theory of Neuronal Systems” at the Max Planck Institute for Dynamics and Self Organization (MPI-DS) and at
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03.10.2022

Seeded Binary Segmentation: A general methodology for fast andoptimal change point detection

Authors Kovács S, Li H, Bühlmann P, Munk A Journal Biometrika Citation Biometrika, 2022, asac052. Abstract We propose seeded binary segmentation for large scale changepoint detection problems. We construct a deterministic set of background intervals, called seeded intervals, in which single changepoint candidates are searched for. The final selection of
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