Susann Meyer

01.06.2025

Nat Commun

01.06.2025

Anle138b binds predominantly to the central cavity in lipidic Aβ₄₀ fibrils and modulates fibril formation

Han M, Frieg B, Matthes D, Leonov A, Ryazanov S, Giller K, Nimerovsky E, Stampolaki M, Xue K, Overkamp K, Dienemann C, Riedel D, Giese A, Becker S, de Groot BL, Schröder GF, Andreas LB, Griesinger C

29.05.2025

J R Stat Soc Series B: Stat Method

29.05.2025

Detection and inference of changes in high-dimensional linear regression with non-sparse structures

Cho H, Kley T, Li H

28.05.2025

Legend: 3D reconstruction of the myoferlin structure from cryo-EM datasets. Upon membrane-binding, a much more compact ring-like arrangement (right) of the various key domains (colored) is achieved compared to the lipid-free myoferlin protein (left). Credit: Cretu/mbexc

28.05.2025

Enigmatic ring carriers: Göttingen researchers uncover the structural secret of the ferline

Researchers from the Göttingen Cluster of Excellence Mutliscale Bioimaging (MBExC) have uncovered the 3D structure of the membrane proteins myoferlin and dysferlin using high-resolution cryo-electron microscopy. The findings enable new […]

28.05.2025

Legend: 3D reconstruction of the myoferlin structure from cryo-EM datasets. Upon membrane-binding, a much more compact ring-like arrangement (right) of the various key domains (colored) is achieved compared to the lipid-free myoferlin protein (left). Credit: Cretu/mbexc

28.05.2025

Enigmatic ring carriers Göttingen researchers uncover the structural secret of the ferline

Researchers from the Göttingen Cluster of Excellence Mutliscale Bioimaging (MBExC) have uncovered the 3D structure of the membrane proteins myoferlin and dysferlin using high-resolution cryo-electron microscopy. The findings enable new […]

28.05.2025

Proc Natl Acad Sci U S A

28.05.2025

Myricetin-bound crystal structure of the SARS-CoV-2 helicase NSP13 facilitates the discovery of novel natural inhibitors

Kloskowski P, Neumann P, Kumar P, Berndt A, Dobbelstein M, Ficner R

28.05.2025

EMBO J

28.05.2025

Structural insights into lipid membrane binding by human ferlins

Cretu C, Chernev A, Szabo CZK, Pena V, Urlaub H, Moser T, Preobraschenski J

Anle138b binds predominantly to the central cavity in lipidic Aβ₄₀ fibrils and modulates fibril formation

Detection and inference of changes in high-dimensional linear regression with non-sparse structures

Enigmatic ring carriers: Göttingen researchers uncover the structural secret of the ferline

Enigmatic ring carriers Göttingen researchers uncover the structural secret of the ferline

Myricetin-bound crystal structure of the SARS-CoV-2 helicase NSP13 facilitates the discovery of novel natural inhibitors

Structural insights into lipid membrane binding by human ferlins

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