Susann Meyer

14.04.2022

Indicated are the intracellular steps of the Gq signaling cascade, which can now be controlled by scientists using light to drive activity in transgenic mouse hearts (left) and contractions in the small intestine (right). Source: Prof. Brügmann / umg.

14.04.2022

A new tool for optogenetics: human receptor for studying cell function with light

Scientists of the University Medical Center Göttingen identify the human OPN5 receptor as a new target to activate cells and to study the principles of how cells communicate with each […]

13.04.2022

Sci Transl Med

13.04.2022

Tissue-resident memory CD8+ T cells cooperate with CD4+ T cells to drive compartmentalized immunopathology in the CNS

Vincenti I, Page N, Steinbach K, Yermanos A, Lemeille S, Nunez N, Kreutzfeldt M, Klimek B, Di Liberto G, Egervari K, Piccinno M, Shammas G, Mariotte A, Fonta N, Liaudet N, Shlesinger D, Liuzzi AR, Wagner I, Saadi C, Stadelmann C, Reddy S, Becher B, Merkler D

07.04.2022

Chem Methods

07.04.2022

Rapidly Signal-enhanced Metabolites for Atomic Scale Monitoring of Living Cells with Magnetic Resonance

Ding Y, Korchak S, Mamone S, Jagtap AP, Stevanato G, Sternkopf S, Moll D, Schroeder H, Becker S, Fischer A, Gerhardt E, Outeiro TF, Opazo F, Griesinger C, Glöggler S

04.04.2022

J Biol Chem

04.04.2022

The small aromatic compound SynuClean-D inhibits the aggregation and seeded polymerization of multiple α-synuclein strains

Peña-Díaz S, Pujols J, Vasili E, Pinheiro F, Santos J, Manglano-Artuñedo Z, Outeiro TF, Ventura S

01.04.2022

Nat Commun

01.04.2022

Selective optogenetic control of Gq signaling using human Neuropsin

Wagdi A, Malan D, Sathyanarayanan U, Beauchamp JS, Vogt M, Zipf D, Beiert T, Mansuroglu B, Dusend V, Meininghaus M, Schneider L, Kalthof B, Wiegert JS, König GM, Kostenis E, Patejdl R, Sasse P, Bruegmann T

29.03.2022

Trends Biochem Sci