Susann Meyer

02.05.2022

The figure shows a cell with excessive alpha-synuclein (left) compared to a cell, where alpha-synuclein was genetically switched off (right). The cell nucleus is colored blue, the protein alpha-synuclein yellow.© Felipe Opazo / UMG

02.05.2022

Possible biomarker for Parkinson’s discovered using new MRI method

Researchers and MBExC members at the Max Planck Institute (MPI) for Multidisciplinary Sciences, the University Medical Center Göttingen (UMG), and the German Center for Neurodegenerative Diseases (DZNE) have used this insight in a first step to develop a new diagnostics approach.

02.05.2022

J Clin Invest

02.05.2022

HAX1-dependent control of mitochondrial proteostasis governs neutrophil granulocyte differentiation

Fan Y, Murgia M, Linder MI, Mizoguchi Y, Wang C, Łyszkiewicz M, Ziȩtara N, Liu Y, Frenz S, Sciuccati G, Partida-Gaytan A, Alizadeh Z, Rezaei N, Rehling P, Dennerlein S, Mann M, Klein C

25.04.2022

NPJ Parkinsons Dis

25.04.2022

Glycation modulates glutamatergic signaling and exacerbates Parkinson’s disease-like phenotypes

Chegão A, Guarda M, Alexandre BM, Shvachiy L, Temido-Ferreira M, Marques-Morgado I, Fernandes Gomes B, Matthiesen R, Lopes LV, Florindo PR, Gomes RA, Gomes-Alves P, Coelho JE, Outeiro TF, Vicente Miranda H

21.04.2022

Int J Mol Sci

21.04.2022

A Reliable Approach for Revealing Molecular Targets in Secondary Ion Mass Spectrometry

Li F, Fornasiero EF, Dankovich TM, Kluever V, Rizzoli SO

15.04.2022

Sci Adv

15.04.2022

Cln5 represents a new type of cysteine-based S-depalmitoylase linked to neurodegeneration

Luebben AV, Bender D, Becker S, Crowther LM, Erven I, Hofmann K, Söding J, Klemp H, Bellotti C, Stäuble A, Qiu T, Kathayat RS, Dickinson BC, Gärtner J, Sheldrick GM, Krätzner R, Steinfeld R

14.04.2022

Indicated are the intracellular steps of the Gq signaling cascade, which can now be controlled by scientists using light to drive activity in transgenic mouse hearts (left) and contractions in the small intestine (right). Source: Prof. Brügmann / umg.

14.04.2022

A new tool for optogenetics: human receptor for studying cell function with light

Scientists of the University Medical Center Göttingen identify the human OPN5 receptor as a new target to activate cells and to study the principles of how cells communicate with each […]