Research team optimises microscope with innovative technology to benefit research and medicine
Light sheet microscopy produces impressive 3D images of tissue and entire organs, such as the delicate cochlea in the inner ear or the complex brain of a mouse. A thin layer of light, the light sheet, moves through the sample and generates a three-dimensional image layer by layer. However, larger samples create problems for conventional microscopes: the process is slow and the images blurred. This led researchers in Göttingen to develop a technologically innovative light sheet fluorescence microscopy platform that improves imaging and opens up new opportunities for research and medicine. Detailed scans allow, for example, fine networks of nerves or blood vessels to be examined in greater detail. The research team at the University of Göttingen and the University Medical Center Göttingen (UMG), worked in collaboration with the University of Lübeck as part of the Göttingen Cluster of Excellence “Multiscale Bioimaging: From Molecular Machines to Networks of Excitable Cells” (MBExC). The results were published in Nature Biotechnology.
You can find the press release here.
From left to right: Dr. Mostafa Aakhte, Dr. Lennart Roos, Aleyna M. Diniz, Prof. Dr. Jan Huisken. Photo: Tobias Moser
