Susann Meyer

05.08.2020

CRISPR/Cas9-repaired iPSC-cardiomyocytes display a restored function and a normalized muscle contraction.
© Cyganek, UMG

05.08.2020

CRISPR/Cas9 – GENE EDITING: Neuer Therapieansatz für angeborene Herzfehler

Wissenschaftler am Herzzentrum der Universitätsmedizin Göttingen haben erstmals einen Ansatz für eine personalisierte Therapieoption mit „Gene Editing“ für das Noonan-Syndrom gefunden. Veröffentlicht in der renommierten Fachzeitschrift „Circulation„. Link zur Pressemitteilung […]

05.08.2020

CRISPR/Cas9-repaired iPSC-cardiomyocytes display a restored function and a normalized muscle contraction.
© Cyganek, UMG

05.08.2020

CRISPR/Cas9 – GENE EDITING: New therapeutic approach for congenital heart defects

Scientists at the Heart Center of the University Medical Center Göttingen have for the first time found an approach for a personalised therapy option with „gene editing“ for the Noonan […]

01.08.2020

Remyelination in multiple sclerosis: from basic science to clinical translation

Lubetzki C, Zalc B, Williams A, Stadelmann C, Stankoff B

30.07.2020

Dopamine promotes the neurodegenerative potential of β-synuclein

Raina A, Leite K, Guerin S, Mahajani SU, Chakrabarti KS, Voll D, Becker S, Griesinger C, Bähr M, Kügler S

30.07.2020

Effects of pharmacological modulators of α‐synuclein and tau aggregation and internalization

Dominguez-Meijide A, Vasili E, König A, Cima-Omori MS, Ibáñez de Opakua A, Leonov A, Ryazanov S, Zweckstetter M, Griesinger C, Outeiro TF

30.07.2020

Snapshot of protein mobility in the synapse. A region within the synapse at the edge of the synaptic vesicle cluster is shown.
Organelles in grey represent synaptic vesicles (each ~40 nm in diameter). Various shapes correspond to different protein molecules, with each protein species having its own shape, as extracted from stuctural studies. The proteins are colored based on the speed of movement of every individual molecule in every position, from dark violet (the slowest one) to yellow (the fastest). Most proteins move slowly next to the synaptic vesicles, and are much faster in the vesicle-free region.
Source: Reshetniak and co-authors

30.07.2020

Auf einen Streich: Wie sich Proteine in lebenden Synapsen bewegen

Wissenschaftler*innen des Exzellenzclusters Multiscale Bioimaging gelingt erstmals die simultane Darstellung der Bewegungsprofile einer Vielzahl von Proteinen in der Synapse.