2025

Authors Karagulyan N, Thirumalai A, Michanski S, Qi Y, Fang Q, Wang H, Ortner NJ, Striessnig J, Strenzke N, Wichmann C, Hua Y, Moser T Journal BioRxiv Citation bioRxiv 2025.01.23.634330. Abstract Our sense of hearing processes sound intensities spanning six orders of magnitude. In the ear, postsynaptic spiral ganglion neurons

Authors Eskandari MA, Fischer J, Veyret N, Marx D, Betz T Journal Arxiv Citation arXiv:2501.14538. Abstract While mechanobiology has demonstrated that precise control over mechanical properties at the whole-cell level is crucial for many biological functions, comparatively little attention has been paid to the intracellular mechanical properties. Experimental tools have

Authors Stoldt S, Maass F, Weber M, Dennerlein S, Ilgen P, Gaertner J, Canfes A, Schweighofer SV, Jans DC, Rehling P, Jakobs S Journal BioRxiv Citation bioRxiv 2025.01.23.634455. Abstract Mitochondria contain their own DNA (mtDNA) and a dedicated gene expression machinery. As the mitochondrial dimensions are close to the diffraction

Authors Liu Y, Müller G, Kowitz L, Chobola T, Weiss K, Maier P, Luo J, Roeßing M, Stenzel M, Grüneboom A, Paetzold J, Ertürk A, Navab N, Marr C, Chen J, Huisken J, Peng T Journal Research Square Citation Research Square 2025. Abstract Selective plane illumination microscopy (SPIM, also known

Authors Cotroneo ER, Cheng TC, Kaltschnee L, Maibach P, Engelke M, Schwegler N, Thomas F, Thiele CM, Simeth N Journal ChemRxiv Citation ChemRxiv. 2025. Abstract Peptides and proteins, that have the tendency to form aggregates, are often discussed in the context of Alz-heimer’s, Huntington’s, or Parkinson’s disease. However, studying aggregation

Authors Maestro-Lopez M, Cheng TC, Muntaner J, Menendez M, Alonso M, Schweitzer A, Cuellar J, Valpuesta JM, Sakata E Journal BioRxiv Citation bioRxiv 2025.01.22.633148. Abstract The 26S proteasome primarily degrades proteins marked by polyubiquitin chains. Although ubiquitin-independent pathways for proteasomal degradation exist, the mechanisms involved remain poorly understood. Bag1 links

Authors Jimenez AJ, Isensee J, Hofemeier A, Krueger LJ, Wittkowski R, Golestanian R, Bittihn P, Betz T Journal BioRxiv Citation bioRxiv 2025.01.22.633835. Abstract The measurement of stresses and forces at the tissue level has proven to be an indispensable tool for the understanding of complex biological phenomena such as cancer

Authors Frohn J, Böddeker F, Reichardt M, Bruns H, Czajka T, Khan A, Broche L, Krisch M, Bravin A, Alves F, Zschüntzsch J, Salditt T Journal Scientific Reports Citation Sci Rep. 2025 Jan 22;15(1):2766. Abstract Imaging the entire cardiomyocyte network in entire small animal hearts at single cell resolution is

Authors Requardt R, Fink M, Kubica P, Steinem C, Munk A, Li H   Journal IEEE Transactions on NanoBioScience (TNB)   Citation IEEE Transactions on NanoBioScience (TNB). 2025.   Abstract Recent experimental studies have shed light on the intriguing possibility that ion channels exhibit cooperative behaviour. However, a comprehensive understanding

Authors Archit A, Freckmann L, Pape C Journal Arxiv Citation arXiv:2501.11734. Abstract Medical image segmentation is an important analysis task in clinical practice and research. Deep learning has massively advanced the field, but current approaches are mostly based on models trained for a specific task. Training such models or adapting