2024

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06.06.2024

Open Problem: Active Representation Learning

Authors Milosevic N, Müller G, Huisken J, Scherf N Journal Arxiv Citation arXiv:2406.03845. Abstract In this work, we introduce the concept of Active Representation Learning, a novel class of problems that intertwines exploration and representation learning within partially observable environments. We extend ideas from Active Simultaneous Localization and Mapping (active
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04.06.2024

Effective exosomes reduction in hypercholesterinemic patients suffering from cardiovascular diseases by lipoprotein apheresis: Exosomes apheresis

Authors Schröder S, Epple R, Fischer A, Schettler VJJ Journal Therapeutic Apheresis and Dialysis Citation Ther Apher Dial. 2024 Jun 4. Abstract Introduction: Extracellular vesicles (EVs) have been identified as playing a role in atherosclerosis. Methods: A group of 37 hypercholesterolemic patients with atherosclerotic cardiovascular diseases (ASCVD) and 9 patients
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03.06.2024

The COMBO window: A chronic cranial implant for multiscale circuit interrogation in mice

Authors Edelman BJ, Siegenthaler D, Wanken P, Jenkins B, Schmid B, Ressle A, Gogolla N, Frank T, Macé E Journal Plos Biology Citation PLOS Biology 22(6): e3002664. Abstract Neuroscientists studying the neural correlates of mouse behavior often lack access to the brain-wide activity patterns elicited during a specific task of
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03.06.2024

Catching up but still miles behind — a patient registry for otoferlin

Authors Vona B, Wollnik B, Strenzke N, Moser T Journal Experimental & Molecular Medicine Citation Exp Mol Med (2024). Abstract No abstract available. DOI 10.1038/s12276-024-01247-6   Pubmed Link
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01.06.2024

Analyzing cross-talk between superimposed signals: Vector norm dependent hidden Markov models and applications to ion channels

Authors Vanegas LJ, Eltzner B, Rudolf D, Dura M, Lehnart SE, Munk A Journal The Annals of Applied Statistics Citation Ann. Appl. Stat. 18(2): 1445-1470. Abstract We propose and investigate a hidden Markov model (HMM) for the analysis of dependent, aggregated, superimposed two-state signal recordings. A major motivation for this
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01.06.2024

Through the Haze: Unveiling the Link Between Smoking and Atrial Fibrillation

Authors Mason FE, Voigt N Journal American Journal of Physiology. Heart and Circulatory Physiology Citation Am J Physiol Heart Circ Physiol. 2024 Jun 1;326(6):H1489-H1490. Abstract No abstract available. DOI 10.1152/ajpheart.00286.2024   Pubmed Link
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01.06.2024

Characterizing intracellular mechanics via optical tweezers-based microrheology

Authors Vos BE, Muenker TM, Betz T Journal Current Opinion in Cell Biology Citation Curr Opin Cell Biol. 2024 Jun 1;88:102374. Abstract Intracellular organization is a highly regulated homeostatic state maintained to ensure eukaryotic cells’ correct and efficient functioning. Thanks to decades of research, vast knowledge of the proteins involved
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30.05.2024

Metabolic remodelling in atrial fibrillation: manifestations, mechanisms and clinical implications

Authors Bode D, Pronto JRD, Schiattarella GG, Voigt N Journal Nature Reviews. Cardiology Citation Nat Rev Cardiol. 2024 May 30. Abstract Atrial fibrillation (AF) is a continually growing health-care burden that often presents together with metabolic disorders, including diabetes mellitus and obesity. Current treatments often fall short of preventing AF
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29.05.2024

Intracellular mechanical fingerprint reveals cell type specific mechanical tuning

Authors Muenker TM, Vos BE, Betz T Journal eLife Citation eLife13:RP97416. Abstract Living cells are complex entities that perform many different complex tasks with astonishing robustness. While the direct dependence of biological processes on controlled protein expression is well established, we only begin to understand how intracellular mechanical characteristics guide
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Direktor*innen der ausgewählten DZKJ-Partnerstandorte (v.l.n.r.): Prof. Dr. Klaus-Michael Debatin (Ulm und stellvertretender Sprecher DZKJ), Prof. Dr. Neeltje van den Berg (Greifswald/Rostock), Prof. Dr. Antje Körner (Leipzig/Dresden), Prof. Dr. Christoph Klein (München), Prof. Dr. Ania Muntau (Hamburg), Prof. Dr. Marcus Mall (Berlin), Prof. Dr. Jutta Gärtner (Göttingen und Sprecherin DZKJ). Foto: UMG/Simone Schröder

29.05.2024

DZKJ startet in die Aufbauphase

Deutsches Zentrum für Kinder- und Jugendgesundheit (DZKJ) wird ab 1. Juni 2024 neuer Partner der Deutschen Zentren der Gesundheitsforschung (DZG). Das bundesweit organisierte und vernetzte Forschungszentrum wird während der zweijährigen Aufbauphase mit 30 Millionen Euro vom Bundesministerium für Bildung und Forschung gefördert. Die DZKJ-Geschäftsstelle wird an der Universitätsmedizin Göttingen (UMG)
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