29.03.2024
Authors Maurer W, Rebs S, Köhne S, Eberl H, Wollnik B, Zibat A, Streckfuss-Bömeke K Journal Stem Cell Research Citation Stem Cell Res. 2024 Mar 29;77:103409. Abstract Filamin C (FLNC) is a highly important actin crosslinker and multi-adaptor protein in striated skeletal and cardiac muscle. Mutations have been linked to
29.03.2024
Label-free quantification of imaging features in the extracellular matrix of left and right-sided colon cancer tissues
Authors Arora B, Kulkarni A, Markus MA, Ströbel P, Bohnenberger H, Alves F, Ramos-Gomes F Journal Scientific Reports Citation Sci Rep. 2024 Mar 29;14(1):7510. Abstract The molecular pathogenesis of colorectal cancer is known to differ between the right and left side of the colon. Several previous studies have focussed on
27.03.2024
Dynamic Gain Decomposition Reveals Functional Effects of Dendrites, Ion Channels, and Input Statistics in Population Coding
Authors Zhang C, Revah O, Wolf F, Neef A Journal Journal of Neuroscience Citation J Neurosci. 2024 Mar 27;44(13):e0799232023. Abstract Modern, high-density neuronal recordings reveal at ever higher precision how information is represented by neural populations. Still, we lack the tools to understand these processes bottom-up, emerging from the biophysical
27.03.2024
Chemical synthesis of site-selective advanced glycation end products in α-synuclein and its fragments
Authors Bosbach C, Gatzemeier LM, Bloch von Blottnitz KI, König A, Diederichsen U, Steinem C, Outeiro TF Journal Organic & Biomolecular Chemistry Citation Org Biomol Chem. 2024 Mar 27;22(13):2670-2676. Abstract Advanced glycation end products (AGEs) arise from the Maillard reaction between dicarbonyls and proteins, nucleic acids, or specific lipids. Notably,
27.03.2024
Formation of memory assemblies through the DNA-sensing TLR9 pathway
Authors Jovasevic V, Wood EM, Cicvaric A, Zhang H, Petrovic Z, Carboncino A, Parker KK, Bassett TE, Moltesen M, Yamawaki N, Login H, Kalucka J, Sananbenesi F, Zhang X, Fischer A, Radulovic J Journal Nature Citation Nature. 2024 Apr;628(8006):145-153. Abstract As hippocampal neurons respond to diverse types
25.03.2024
Regulation of Zbp1 by miR-99b-5p in microglia controls the development of schizophrenia-like symptoms in mice
Authors Kaurani L, Islam MR, Heilbronner U, Krüger DM, Zhou J, Methi A, Strauss J, Pradhan R, Schröder S, Burkhardt S, Schuetz AL, Pena T, Erlebach L, Bühler A, Budde M, Senner F, Kohshour MO, Schulte EC, Schmauß M, Reininghaus EZ, Juckel G, Kronenberg-Versteeg D, Delalle I, Odoardi F, Flügel
25.03.2024
Gene therapy for deafness: are we there now?
Authors Moser T, Chen H, Kusch K, Behr R, Vona B Journal EMBO Molecular Medicine Citation EMBO Mol Med. 2024 Mar 25. Abstract No abstract available. DOI 10.1038/s44321-024-00058-6 Pubmed Link
22.03.2024
Wissenschaftsminister Falko Mohrs besucht Göttinger Exzellenzcluster
Falko Mohrs, Niedersächsischer Minister für Wissenschaft und Kultur, hat die Forschenden des Göttinger Exzellenzclusters „Multiscale Bioimaging: Von molekularen Maschinen zu Netzwerken erregbarer Zellen“ (MBExC) am Freitag, 22. März 2024, besucht. Anlass war der im August einzureichende Fortsetzungsantrag von MBExC, um sich im Rahmen der Exzellenzstrategie für eine Förderung für weitere
22.03.2024
Wissenschaftsminister Falko Mohrs besucht Göttinger Exzellenzcluster
Falko Mohrs, Niedersächsischer Minister für Wissenschaft und Kultur, hat die Forschenden des Göttinger Exzellenzclusters „Multiscale Bioimaging: Von molekularen Maschinen zu Netzwerken erregbarer Zellen“ (MBExC) am Freitag, 22. März 2024, besucht. Anlass war der im August einzureichende Fortsetzungsantrag von MBExC, um sich im Rahmen der Exzellenzstrategie für eine Förderung für weitere
22.03.2024
Gender-Specific Effects on the Cardiorespiratory System and Neurotoxicity of Intermittent and Permanent Low-Level Lead Exposures
Authors Shvachiy L, Amaro-Leal Â, Machado F, Rocha I, Outeiro TF, Geraldes V Journal Biomedicines Citation Biomedicines. 2024 Mar 22;12(4):711. Abstract Lead exposure is a significant health concern, ranking among the top 10 most harmful substances for humans. There are no safe levels of lead exposure, and it affects multiple