2023 – Seite 23

19.01.2023

Graded optogenetic activation of the auditory pathway for hearing restoration

Authors Mittring A, Moser T, Huet AT Journal Brain Stimulation Citation Brain Stimul. 2023 Jan 23:S1935-861X(23)01673-X. Abstract Optogenetic control of neural activity enables innovative approaches to improve functional restoration of diseased sensory and motor systems. For clinical translation to succeed, optogenetic stimulation needs to closely match the coding properties of

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18.01.2023

Impact of the Euro 2020 championship on the spread of COVID-19

Authors Dehning J, Mohr SB, Contreras S, Dönges P, Iftekhar EN, Schulz O, Bechtle P, Priesemann V Journal Nature Communications Citation Nat Commun 14, 122 (2023). Abstract Large-scale events like the UEFA Euro 2020 football (soccer) championship offer a unique opportunity to quantify the impact of gatherings on the spread

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15.01.2023

Uncovering the molecular link between lead toxicity and Parkinson’s disease

Authors Shvachiy L, Geraldes V, Outeiro TF Journal Antioxidants & Redox Signaling Citation Antioxidants & Redox Signaling. 2023. Abstract Parkinson’s disease (PD) is a progressive neurodegenerative disorder that affects millions around the world. The etiology of PD remains unknown, but environmental and ocuppational exposures to heavy metals are likely at

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10.01.2023

Gilles Mordant awarded annual prize

Mathematician and data scientist Dr. Gilles Mordant from the Institute for Mathematical Stochastics at the University of Göttingen, headed by MBExC-member Prof. Dr. Axel Munk, has received the prize for the Annual Contest (section mathematics) of the Royal Academy of Science, Letters and Fine Arts of Belgium. The prize is

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10.01.2023

Translation Factor Accelerating Peptide Bond Formation on the Ribosome: EF-P and eIF5A as Entropic Catalysts and a Potential Drug Targets

Authors Mudryi V, Peske F, Rodnina M Journal BBA Advances Citation BBA Advances (2023). Abstract Elongation factor P (EF-P) and its eukaryotic homolog eIF5A are auxiliary translation factors that facilitate peptide bond formation when several sequential proline (Pro) residues are incorporated into the nascent chain. EF-P and eIF5A bind to

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10.01.2023

Trafficking proteins show limited differences in mobility across different postsynaptic spines

Authors Mougios N, Opazo F, Rizzoli SO, Reshetniak S Journal iScience Citation iScience (2023). Abstract The function of the postsynaptic compartment is based on the presence and activity of postsynaptic receptors, whose dynamics are controlled by numerous scaffolding, signaling and trafficking proteins. While the receptors and the scaffolding proteins have

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04.01.2023

Multimodal epigenetic changes and altered NEUROD1 chromatin binding in the mouse hippocampus underlie FOXG1 syndrome

Authors Akol I, Izzo A, Gather F, Strack S, Heidrich S, Ó hAilín D, Villarreal A, Hacker C, Rauleac T, Bella C, Fischer A, Manke T, Vogel T Journal Proceedings of the National Academy of Sciences of the United States of America Citation Proc Natl Acad Sci U S A.

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02.01.2023

Das MBExC begrüßt Nachwuchsgruppenleiter Dr. Thomas Frank

Mit Beginn des neuen Jahres übernimmt Neurowissenschaftler Dr. Thomas Frank die Leitung der Nachwuchsforschungsgruppe für Zebrafisch-Neurobiologie am Göttinger Exzellenzcluster MBExC. Gemeinsam mit seinem Team untersucht er, wie das Gehirn Gerüche verarbeitet und wie dies zu bestimmten Handlungen und flexiblen Verhaltensweisen führt. Die neuronale Informationsverarbeitung auf verschiedenen Ebenen, von Synapsen bis

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