März

Home >> 2022 >> März
Feature image not available
31.03.2022

Extracellular Matrix Recycling as a Novel Plasticity Mechanism With a Potential Role in Disease

Authors Dankovich TM, Rizzoli SO Journal Frontiers in Cellular Neuroscience Citation Front Cell Neurosci. 2022 Mar 31;16:854897. Abstract The extracellular matrix (ECM) stabilizes neural circuits and synapses in the healthy brain, while also retaining the ability to be remodeled, to allow synapses to be plastic. A well-described mechanism for ECM
Learn More
Feature image not available
29.03.2022

Roles and dynamics of 3-methylcytidine in cellular RNAs

Authors Bohnsack KE, Kleiber N, Lemus-Diaz N, Bohnsack MT Journal Trends in Biochemical Sciences Citation Trends Biochem Sci. 2022 Mar 29:S0968-0004(22)00063-9. Abstract Modified nucleotides within cellular RNAs significantly influence their biogenesis, stability, and function. As reviewed here, 3-methylcytidine (m3C) has recently come to the fore through the identification of the
Learn More

Weißbüschelaffe (Callithrix jacchus), Weibchen, 3 Jahre alt, Foto: Charis Drummer

28.03.2022

Töne zum Anfassen

Ein Forscherteam unter der Leitung von Marcus Jeschke am Deutschen Primatenzentrum – Leibniz-Institut für Primatenforschung (DPZ) und am Institut für Auditorische Neurowissenschaften unter der Leitung von MBExC Mitglied Tobias Moser am Universitätsklinikum Göttingen hat ein automatisiertes Hör-Trainingsprogramm entwickelt, an dem Weißbüschelaffen freiwillig und in gewohnter Umgebung teilnehmen können. Dem Team
Learn More
Feature image not available
28.03.2022

Flexible auditory training, psychophysics, and enrichment of common marmosets with an automated, touchscreen-based system

Authors Calapai A, Cabrera-Moreno J, Moser T, Jeschke M Journal Nature Communications Citation Nat Commun. 2022 Mar 28;13(1):1648. Abstract Devising new and more efficient protocols to analyze the phenotypes of non-human primates, as well as their complex nervous systems, is rapidly becoming of paramount importance. This is because with genome-editing
Learn More

Das Bild ist eine künstlerische Nachbearbeitung einer lichtmikroskopischen Aufnahme, die das Innere einer Nervenzellendung zeigt. Türkise, rote und gelbe Kreise stellen Vesikel dar, die jeweils Transporter für Glutamat, Zink oder beides enthalten. Die Zentren der roten Linien zeigen an, wo die Botenstoffe die Nervenzelle verlassen. © Dr. Radhika Patnala, Sci-Illustrate

22.03.2022

Warum manche Nervenzellen mehr zu sagen haben

Nervenzellen kommunizieren miteinander über chemische Botenstoffe, die in Bläschen – den synaptischen Vesikeln – gespeichert sind. Dabei sind einige dieser Zellen „wortgewandter“ als andere; sie können mehr als eine Art von Botenstoff aussenden. Über welche Mechanismen diese „mehrsprachige“ Kommunikation im Gehirn erfolgt, war jedoch bisher ein Rätsel. Forschende am Max-Planck-Institut
Learn More
Feature image not available
21.03.2022

Stage-specific control of oligodendrocyte survival and morphogenesis by TDP-43

Authors Heo D, Ling JP, Molina-Castro GC, Langseth AJ, Waisman A, Nave KA, Möbius W, Wong PC, Bergles DE Journal Elife Citation eLife. 2022 Mar 21;11:e75230. Abstract Generation of oligodendrocytes in the adult brain enables both adaptive changes in neural circuits and regeneration of myelin sheaths destroyed by injury, disease,
Learn More
Feature image not available
18.03.2022

Glycation modulates alpha-synuclein fibrillization kinetics: a sweet spot for inhibition

Authors Farzadfard A, König A, Petersen SV, Nielsen J, Vasili E, Dominguez-Meijide A, Buell AK, Outeiro TF, Otzen DE Journal Journal of Biological Chemistry Citation J Biol Chem. 2022 Mar 18:101848. Abstract Glycation is a nonenzymatic posttranslational modification (PTM) known to be increased in the brains of hyperglycemic patients. Alpha-synuclein
Learn More
Feature image not available
12.03.2022

Autosomal dominant non-syndromic hearing loss maps to DFNA33 (13q34) and co-segregates with splice and frameshift variants in ATP11A, a phospholipid flippase gene

Authors Pater JA, Penney C, O’Rielly DD, Griffin A, Kamal L, Brownstein Z, Vona B, Vinkler C, Shohat M, Barel O, French CR, Singh S, Werdyani S, Burt T, Abdelfatah N, Houston J, Doucette LP, Squires J, Glaser F, Roslin NM, Vincent D, Marquis P, Woodland G, Benoukraf T, Hawkey-Noble
Learn More
Feature image not available
11.03.2022

Methods for multiscale structural and functional analysis of the mammalian cochlea

Authors Vogl C, Neef J, Wichmann C Journal Molecular and Cellular Neuroscience Citation Mol Cell Neurosci. 2022 Mar 11;120:103720. Abstract The mammalian cochlea is a snail-shaped structure deeply that is embedded in the temporal bone and harbors the auditory sensory epithelium – the organ of Corti. Since the discovery of
Learn More
Feature image not available
10.03.2022

A mathematical model for electrical activity in pig atrial tissue

Authors Peris-Yagüe V, Rubio T, Fakuade FE, Voigt N, Luther S, Majumder R Journal Frontiers in Physiology Citation Front Physiol. 2022 Mar 10;13:812535. Abstract State of the art mathematical models are currently used to bridge the gap between basic research conducted in the laboratory and preclinical research conducted on large
Learn More
X
EN DE
X
X