2025

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08.08.2025

Update on Gastric Pacemaking: Relevance for Gastroparesis

Authors Riebeling J, Patejdl R, Zipf D, Conradi LC, Ghadimi M, Gundling F, Bruegmann T. Journal Zentralblatt für Chirurgie Citation Zentralbl Chir. 2025 Aug;150(4):337-345. German. Abstract Gastroparesis is a disease in which gastric emptying is significantly decreased in the absence of a mechanical obstruction of the gastric outlet. In addition
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06.08.2025

Microglia-neuron crosstalk via Hex-GM2-MGL2 maintains brain homeostasis

Authors Frosch M, Shimizu T, Wogram E, Amann L, Gruber L, Groisman AI, Fliegauf M, Schwabenland M, Chhatbar C, Zechel S, Rosewich H, Gärtner J, Quintana FJ, Buescher JM, Blank T, Binder H, Stadelmann C, Letzkus JJ, Hopf C, Masuda T, Knobeloch KP, Prinz M Journal Nature Citation Nature. 2025
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Prof. Dr. Diethelm Wolfgang Richter. Photo: private.

04.08.2025

Obituary for Prof. Dr. Diethelm Wolfgang Richter

Prof. Dr. Diethelm Wolfgang Richter, former director of the Institute of Neuro- and Sensory Physiology at the University Medical Center Göttingen (UMG), passed away on 23 July 2025 at the age of 81. Prof. Richter held the university professorship for Neuro- and Sensory Physiology at the Medical Faculty of the
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02.08.2025

Hierarchically ordered multi-timescale structural dynamics of the intrinsically disordered p53 transactivation domain

Authors Szöllősi D, Pratihar S, Mukhopadhyay D, Rout AK, Reddy GJ, Ebersberger N, Becker S, Nagy G, Rauscher S, Lee D, Klement R, Griesinger C, Grubmüller H Journal BioRxiv Citation bioRxiv 2025.08.01.668138 Abstract Intrinsically disordered proteins (IDPs) exhibit pronounced structural dynamics, which is crucial for their functional versatility. Yet their
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01.08.2025

Local Poisson Deconvolution for Discrete Signals

Authors Hundrieser S, Manole T, Litskevich D, Munk A Journal Arxiv Citation arXiv:2508.00824. Abstract We analyze the statistical problem of recovering an atomic signal, modeled as a discrete uniform distribution μ, from a binned Poisson convolution model. This question is motivated, among others, by super-resolution laser microscopy applications, where precise
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01.08.2025

Hearing restoration by a low-weight power-efficient multichannel optogenetic cochlear implant system

Authors Jablonski L, Harczos T, Wolf B, Hoch G, Khurana L, Dieter A, Roos L, Hessler R, Ayub S, Ruther P, Moser T Journal Journal of Neural Engineering Citation J Neural Eng. 2025 Aug 1;22(4). Abstract Objective. In case of deafness, electrical cochlear implants (eCIs) bypass dysfunctional or lost hair
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28.07.2025

Improved “molecular light switch” promises help for blind, deaf and heart patients

Reliable and gentler control of cellular activity with light: Researchers at the Cluster of Excellence Multiscale Bioimaging (MBExC) and the Else Kröner Fresenius Center for Optogenetic Therapies (EKFZ OT) of the University Medical Center Göttingen (UMG) have developed a light-sensitive protein that can restore vision and hearing and regulate the
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28.07.2025

Improved “molecular light switch” promises help for blind, deaf and heart patients

Reliable and gentler control of cellular activity with light: Researchers at the Cluster of Excellence Multiscale Bioimaging (MBExC) and the Else Kröner Fresenius Center for Optogenetic Therapies (EKFZ OT) of the University Medical Center Göttingen (UMG) have developed a light-sensitive protein that can restore vision and hearing and regulate the
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28.07.2025

Efficient and sustained optogenetic control of sensory and cardiac systems

Authors Alekseev A, Hunniford V, Zerche M, Jeschke M, El May F, Vavakou A, Siegenthaler D, Hüser MA, Kiehn SM, Garrido-Charles A, Meyer A, Rambousky A, Alvanos T, Witzke I, Rojas-Garcia KD, Draband MD, Cyganek L, Klein E, Ruther P, Huet A, Trenholm S, Macé E, Kusch K, Bruegmann T,
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24.07.2025

Central limit theorems for the eigenvalues of graph Laplacians on data clouds

Authors Lui C, Trillos NG, Li H, Suchan L Journal Arxiv Citation arXiv:2507.18803. Abstract Given i.i.d.\ samples Xn={x1,…,xn} from a distribution supported on a low dimensional manifold M embedded in Eucliden space, we consider the graph Laplacian operator Δn associated to an ε-proximity graph over Xn and study the asymptotic
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