2025

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14.11.2025

Brain-derived synaptic vesicles have an intrinsic ability to sequester tubulin

Authors Mimoso T, Korobeinikov A, Stein A, Milovanovic D, Rizzoli SO, Köster S, Reshetniak S Journal BMC Biology Citation BMC Biol. 2025 Nov 14;23(1):340. Abstract Background: The presence and function of microtubules within the synaptic bouton has long been under investigation. In recent years, evidence has accumulated that connects the
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13.11.2025

Isotropic, aberration-corrected light sheet microscopy for rapid high-resolution imaging of cleared tissue

Authors Aakhte M, Müller GF, Roos L, Li J, Göpel T, Weiss KR, Diniz AM, Wenzel J, Schwaninger M, Moser T, Huisken J Journal Nature Biotechnology Citation Nat Biotechnol. 2025 Nov 13. Abstract Light-sheet microscopy is ideal for imaging large and cleared tissues, but achieving a high isotropic resolution for
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Cover image of the current issue of the journal Circulation Research: The image shows the regular, blue-stained arrangement of mitochondria in heart muscle cells from the atrium of a patient without cardiac arrhythmia. The cytoskeleton, which supports the structure of the cells and contributes to the orderly organisation of the mitochondria, is shown in magenta. Image: Circulation Research

12.11.2025

Atrial fibrillation: disrupted calcium communication throws the heart out of rhythm

A joint study by Göttingen University Medical Center (UMG) and Würzburg University Hospital provides new insights into why heart muscle cells lose their rhythm in atrial fibrillation. Disrupted calcium communication between central cell structures in the heart could be a decisive mechanism in this process. The findings have been published
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Prof. Dr. Marina Rodnina © Irene Böttcher-Gajewski / Max Planck Institute for Multidisciplinary Sciences

07.11.2025

Millions in funding for research into new mechanisms of translation regulation

The CHAPEROME project, now awarded an ERC Synergy Grant, aims to uncover how molecular folding helpers – known as chaperones – work together with the translation machinery to keep cells functional and adaptable.   Of the 712 proposals submitted for this ERC Synergy Grant call, only 66 projects were selected
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Prof. Dr. Tobias Moser, Director of the Institute for Auditory Neuroscience at University Medical Center Göttingen (UMG), spokesperson at the Göttingen Cluster of Excellence ‘Multiscale Bioimaging: From Molecular Machines to Networks of Excitable Cells’ (MBExC) and spokesperson at the Collaborative Research Center (CRC) 1690 ‘Disease Mechanisms and Functional Restoration of Sensory and Motor Systems’ (left; photo: umg/frank stefan kimmel), and Dr. Rohan Kapoor, former postdoctoral researcher at the Institute for Auditory Neuroscience at UMG (right; photo: umg/rohan kapoor).

06.11.2025

Teamwork in the inner ear: our sense of hearing relies on the organised grouping of proteins

For the first time, researchers at the Göttingen Campus have succeeded in examining the tiny synapses in the inner ear — the contact points between hair cells and auditory nerve cells — at a molecular level. They demonstrated that ion channels and other essential hearing proteins are organised in specific
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05.11.2025

Charting the nanotopography of inner hair cell synapses using MINFLUX nanoscopy

Authors Kapoor R, Kim H, Garlick E, Lima MADRBF, Esch K, Ruhwedel T, Möbius W, Wolf F, Moser T Journal Science Advances Citation Sci. Adv.11,eady4344(2025). Abstract The cochlea encodes sounds into neural signals at the synapses of inner hair cells (IHCs) and spiral ganglion neurons (SGNs) with remarkable fidelity. To
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04.11.2025

Redundancy Maximization as a Principle of Associative Memory Learning

Authors Blümel M, Schneider AC, Neuhaus V, Ehrlich DA, Graetz M, Wibral M, Makkeh A, Priesemann V Journal Arxiv Citation arXiv:2511.02584 Abstract Associative memory, traditionally modeled by Hopfield networks, enables the retrieval of previously stored patterns from partial or noisy cues. Yet, the local computational principles which are required to
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Dr. Christiane Grimm, new MBExC Junior Fellow. Photo: private.

03.11.2025

MBExC Junior Fellow Position for Dr. Christiane Grimm

The MBExC cordially welcomes Dr. Christiane Grimm as new Junior Fellow starting on 3rd November 2025. Her research will focus on “Integrated photonic and genetic tools for all-optical neurophysiology”. Her junior fellow position is affiliated with the Institute for Auditory Neuroscience at the University Medical Center Göttingen.   Link to
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01.11.2025

lncRNA 3222401L13Rik/ENSG00000272070 modulates microglial inflammatory programs in association with PU.1

Authors Pradhan R, Sakib MS, Kaurani L, Krueger DM, Pena T, Burckhardt S, Schuetz AL, Kronenberg-Verstee D, Delalle I, Sananbenesi F, Fischer A Journal BioRxiv Citation bioRxiv 2025.10.31.685723. Abstract Long non-coding RNAs (lncRNAs) are emerging as key regulators of brain function, but their contribution to microglial aging and neurodegenerative disease
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Prof. Dr. Alfons Labisch, Advisory Board Member of the Klüh Foundation, Mayor Dr. Stephan Keller, city of Düsseldorf, Prof. Dr. Jutta Gärtner, award winner, Hans-Joachim Driessen, Chairman of the Klüh Foundation, Roger Klüh, Advisory Board Member of the Klüh Foundation, Prof. Dr. Bettina Rockenbach, laudatory speaker. Photo: Klüh Service Management GmbH/Skaiste Kuß

29.10.2025

Research award for innovative approaches in paediatric neurology

This year, the 25,000 € Klüh Foundation award for the Promotion of Innovation in Science and Research goes to MBExC member Prof. Dr. Jutta Gärtner. The director of the Clinic for Paediatrics and Adolescent Medicine at the University Medical Center Göttingen (UMG) is being honoured for her research into neurometabolic
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