2025

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28.05.2025

Myricetin-bound crystal structure of the SARS-CoV-2 helicase NSP13 facilitates the discovery of novel natural inhibitors

Authors Kloskowski P, Neumann P, Kumar P, Berndt A, Dobbelstein M, Ficner R Journal Acta Crystallographica Section D-Structural Biology Citation Acta Crystallogr D Struct Biol. 2025 Jun 1. Abstract The SARS-CoV-2 helicase NSP13 is a highly conserved and essential component of the viral replication machinery, making it a promising target
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28.05.2025

Structural insights into lipid membrane binding by human ferlins

Authors Cretu C, Chernev A, Szabo CZK, Pena V, Urlaub H, Moser T, Preobraschenski J Journal EMBO Journal Citation EMBO J. 2025 May 28. Abstract Ferlins are ancient membrane proteins with a unique architecture, and play central roles in crucial processes that involve Ca2+-dependent vesicle fusion. Despite their links to
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27.05.2025

Success rates of simulated multi-pulse defibrillation protocols are sensitive to application timing with individual, protocol-specific optimal timings

Authors Aron M, Luther S, Parlitz U Journal Frontiers in Network Physiology Citation Front Netw Physiol. 2025 May 27;5:1572834. Abstract Ventricular fibrillation is a lethal condition where the heartbeat becomes too disorganised to maintain proper circulation. It is treated with defibrillation, which applies an electric shock in an attempt to
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27.05.2025

Toward elucidating the mechanism of cochlear stimulation by infrared light

Authors Moser T, Roos L Journal Proceedings of the National Academy of Sciences of the United States of America Citation Proc Natl Acad Sci U S A. 2025 Jun 3;122(22):e2507582122. Abstract No abstract available. DOI 10.1073/pnas.2507582122   Pubmed Link
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Multiscale Bioimaging at Work. Photo & cover credits: Klein und Neumann, Iserlohn

22.05.2025

Out of the Excellence Strategy competition

The University of Göttingen has been turned down for the Excellence Strategy of the German national and state governments: funding for the Multiscale Bioimaging (MBExC) Cluster of Excellence will not be extended. This was announced today by the Excellence Commission, the joint committee of the German Research Foundation (DFG) and
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Multiscale Bioimaging at Work. Photo & cover credits: Klein und Neumann, Iserlohn

22.05.2025

Out of the Excellence Strategy competition

The University of Göttingen has been turned down for the Excellence Strategy of the German national and state governments: funding for the Multiscale Bioimaging (MBExC) Cluster of Excellence will not be extended. This was announced today by the Excellence Commission, the joint committee of the German Research Foundation (DFG) and
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22.05.2025

Silencing mitochondrial gene expression in living cells

Authors Cruz-Zaragoza LD, Dahal D, Koschel M, Boshnakovska A, Zheenbekova A, Yilmaz M, Morgenstern M, Dohrke JN, Bender J, Valpadashi A, Henningfeld KA, Oeljeklaus S, Kremer LS, Breuer M, Urbach O, Dennerlein S, Lidschreiber M, Jakobs S, Warscheid B, Rehling P Journal Science Citation Science. 2025 May 22:eadr3498. Abstract Mitochondria
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22.05.2025

Endogenous SNAP-tagging of Munc13-1 for monitoring synapse nanoarchitecture

Authors Kowald M, Bachollet SPJT, Benseler F, Steinecker M, Boll M, Kaushik S, Soykan T, Sun S, Birke R, Ilic D, Brose N, Hörnberg H, Lehmann M, Rizzoli SO, Broichhagen J, Lipstein N Journal JACS Au Citation JACS Au 2025. Abstract Synaptic function is governed by highly regulated protein machineries,
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21.05.2025

SMIM20 promotes complex IV biogenesis and Ca2+ signaling in mice heart

Authors Boshnakovska A, Pronto JR, Gall T, Aich A, Prochazka J, Nichtova Z, Sedlacek R, Sobitov I, Ainatzi S, Lenz C, Katschinski DM, Urlaub H, Voigt N, Rehling P, Kremer LS Journal Cell Reports Citation Cell Reports, Volume 44, Issue 6, 115723. Abstract Mitochondria are key to cellular energetics, metabolism,
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Prof. Dr. Timo Betz (Photo: UMG/SPförtner)

21.05.2025

Timo Betz and his team receive audience award in science category

MBExC member Prof. Dr. Timo Betz and his team received the audience award in the science category of the startup competition LIFT-OFF 2025 of the University of Göttingen for their project „ArtifiCell“. The group offers solutions for growing and analysing human 3D miniature tissues in order to test and develop
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