July

Home >> 2025 >> July
28.07.2025

Improved “molecular light switch” promises help for blind, deaf and heart patients

Reliable and gentler control of cellular activity with light: Researchers at the Cluster of Excellence Multiscale Bioimaging (MBExC) and the Else Kröner Fresenius Center for Optogenetic Therapies (EKFZ OT) of the University Medical Center Göttingen (UMG) have developed a light-sensitive protein that can restore vision and hearing and regulate the
Learn More
28.07.2025

Improved “molecular light switch” promises help for blind, deaf and heart patients

Reliable and gentler control of cellular activity with light: Researchers at the Cluster of Excellence Multiscale Bioimaging (MBExC) and the Else Kröner Fresenius Center for Optogenetic Therapies (EKFZ OT) of the University Medical Center Göttingen (UMG) have developed a light-sensitive protein that can restore vision and hearing and regulate the
Learn More
Feature image not available
28.07.2025

Efficient and sustained optogenetic control of sensory and cardiac systems

Authors Alekseev A, Hunniford V, Zerche M, Jeschke M, El May F, Vavakou A, Siegenthaler D, Hüser MA, Kiehn SM, Garrido-Charles A, Meyer A, Rambousky A, Alvanos T, Witzke I, Rojas-Garcia KD, Draband MD, Cyganek L, Klein E, Ruther P, Huet A, Trenholm S, Macé E, Kusch K, Bruegmann T,
Learn More
Feature image not available
24.07.2025

Central limit theorems for the eigenvalues of graph Laplacians on data clouds

Authors Lui C, Trillos NG, Li H, Suchan L Journal Arxiv Citation arXiv:2507.18803. Abstract Given i.i.d.\ samples Xn={x1,…,xn} from a distribution supported on a low dimensional manifold M embedded in Eucliden space, we consider the graph Laplacian operator Δn associated to an ε-proximity graph over Xn and study the asymptotic
Learn More
Feature image not available
22.07.2025

3D multiscale shape analysis of nuclei and in vivo elastic stress sensors allows force inference

Authors Jurado A, Isensee J, Hofemeier A, Krüger LJ, Wittkowski R, Golestanian R, Bittihn P, Betz T Journal Biophysical Journal Citation Biophys J. 2025 Jul 22:S0006-3495(25)00450-3. Abstract The measurement of stresses and forces at the tissue level has proven to be an indispensable tool for the understanding of complex biological
Learn More
Feature image not available
22.07.2025

3D multiscale shape analysis of nuclei and in-vivo elastic stress sensors allows force inference

Authors Jurado A, Isensee J, Hofemeier A, Krüger LJ, Wittkowski R, Golestanian R, Bittihn P, Betz T Journal Biophysical Journal Citation Biophys J. 2025 Jul 22:S0006-3495(25)00450-3. Abstract The measurement of stresses and forces at the tissue level has proven to be an indispensable tool for the understanding of complex biological
Learn More

Prof. Dr. Dr. Tobias Brügmann, University Medical Center Göttingen Photo: MBExC

21.07.2025

New DFG research unit

MBExC member Prof. Dr. Dr. Tobias Brügmann from the University Medical Center Göttingen has helped establish the new DFG research unit, ‘Dynamic Integration of GPCR signaling to control organ function and animal behaviour’. The DFG is funding the group for four years with 5 million euros.   Link to DZHK
Learn More
Feature image not available
19.07.2025

Photoactivatable and Photolabile Pharmacophores: Lessons Learned from Capsaicin

Authors Imse B, Rojas L, Herrero CG, Thallmair S, Rhee JS, Simeth N Journal RSC Chemical Biology Citation RSC Chem Biol. 2025 Jul 19. Abstract Light-controlled molecules have become valuable tools for studying biological systems offering an unparalleled control in space and time. Specifically, the remote-controllable (de)activation of small molecules
Learn More

Professor Timo Betz and Professor Jörg Enderlein, University of Göttingen. Photos: MBExC.

14.07.2025

Timo Betz and Jörg Enderlein received ERC Proof of Concept grants

MBExC members Timo Betz and Jörg Enderlein, both from University of Göttingen,have each been awarded Proof of Concept (PoC) grants by the European Research Council (ERC). These grants provide top-up funding to outstanding researchers, who have already received ERC funding, so that they can build on the innovation potential of
Learn More
Feature image not available
14.07.2025

Circadian clock dysfunction in Parkinson’s disease: mechanisms, consequences, and therapeutic strategy

Authors Yalçin M, Grande V, Outeiro TF, Relόgio A Journal NPJ Parkinsons Disease Citation NPJ Parkinsons Dis. 2025 Jul 14;11(1):213. Abstract Parkinson’s Disease (PD) is a prevalent neurodegenerative disorder characterized by the progressive loss of dopaminergic neurons in the substantia nigra. This leads to hallmark motor features that include bradykinesia,
Learn More
X
EN DE
X
X