2024

Home >> 2024 >> Page 5
Feature image not available
25.10.2024

Increased autonomous bioluminescence emission from mammalian cells by enhanced cofactor synthesis

Authors Brinker T, Gregor C Journal Chemosensors Citation Chemosensors 2024, 12, 223. Abstract The bacterial bioluminescence system has been successfully implemented in mammalian cell lines, enabling the substrate-free luminescence imaging of living cells. One of the major limitations of the system is its comparatively low brightness. To improve light emission,
Learn More
Feature image not available
24.10.2024

Unbiased complexome profiling and global proteomics analysis reveals mitochondrial impairment and potential changes at the intercalated disk in presymptomatic R14Δ/+ mice hearts

Authors Foo B, Amedei H, Kaur S, Jaawan S, Boshnakovska A, Gall T, de Boer RA, Silljé HHW, Urlaub H, Rehling P, Lenz C, Lehnart SE Journal PLoS One Citation PLoS One. 2024 Oct 24;19(10):e0311203. Abstract Phospholamban (PLN) is a sarco-endoplasmic reticulum (SER) membrane protein that regulates cardiac contraction/relaxation by
Learn More

The image shows an egg that has just been ovulated next to the follicle. © Christopher Thomas, Tabea Lilian Marx et al. / Max Planck Institute for Multidisciplinary Sciences

21.10.2024

Ovulation filmed from start to finish for the first time

Approximately 400 times in a woman’s life, a mature egg makes the “leap.” It is released into the fallopian tube, ready for fertilization by the sperm. Researchers led by Melina Schuh, Christopher Thomas, and Tabea Lilian Marx from the Max Planck Institute (MPI) for Multidisciplinary Sciences have now succeeded in
Learn More

The image shows an egg that has just been ovulated next to the follicle. © Christopher Thomas, Tabea Lilian Marx et al. / Max Planck Institute for Multidisciplinary Sciences

21.10.2024

Ovulation filmed from start to finish for the first time

Approximately 400 times in a woman’s life, a mature egg makes the “leap.” It is released into the fallopian tube, ready for fertilization by the sperm. Researchers led by Melina Schuh, Christopher Thomas, and Tabea Lilian Marx from the Max Planck Institute (MPI) for Multidisciplinary Sciences have now succeeded in
Learn More
Feature image not available
21.10.2024

Multiscale scanning with nuisance parameters

Authors König C, Munk A, Werner F Journal Journal of the Royal Statistical Society Series B: Statistical Methodology Citation J R Stat Soc Series B: Statistical Methodology, 2024, 00, 1–19. Abstract We develop a multiscale scanning method to find anomalies in a d-dimensional random field in the presence of nuisance
Learn More
Feature image not available
21.10.2024

Changes in DNA repair compartments and cohesin loss promote DNA damage accumulation in aged oocytes

Authors Sharma N, Coticchio G, Borini A, Tachibana K, Nasmyth KA, Schuh M Journal Current Biology Citation Curr Biol. 2024 Oct 17:S0960-9822(24)01281-8. Abstract Oocyte loss, a natural process that accelerates as women approach their mid-30s, poses a significant challenge to female reproduction. Recent studies have identified DNA damage as a
Learn More
Feature image not available
18.10.2024

Mechanism of polyadenylation-independent RNA polymerase II termination

Authors Rengachari S, Hainthaler T, Oberthuer C, Lidschreiber M, Cramer P Journal Nature Structural & Molecular Biology Citation Nat Struct Mol Biol (2024). Abstract The mechanisms underlying the initiation and elongation of RNA polymerase II (Pol II) transcription are well-studied, whereas termination remains poorly understood. Here we analyze the mechanism
Learn More
Feature image not available
16.10.2024

Addressing SARS-CoV-2 viroporins with antiarrhythmic drugs

Authors Bloothooft M, Voigt N, de Boer TP Journal Europace Citation Europace. 2024 Oct 3;26(10):euae254. Abstract No abstract available. DOI 10.1093/europace/euae254   Pubmed Link
Learn More
Feature image not available
16.10.2024

Ex vivo imaging reveals the spatiotemporal control of ovulation

Authors Thomas C, Marx TL, Penir SM, Schuh M Journal Nature Cell Biology Citation Nat Cell Biol. 2024 Oct 16. Abstract During ovulation, an egg is released from an ovarian follicle, ready for fertilization. Ovulation occurs inside the body, impeding direct studies of its progression. Therefore, the exact mechanisms that
Learn More

Dr. Steffen Sahl (left) and Prof. Dr. Stefan Hell at a MINFLUX microscope. © Irene Böttcher-Gajewski / Max Planck Institute for Multidisciplinary Sciences

10.10.2024

Intra-molecular distances in biomolecules measured optically with Ångström precision

A team led by physicists Steffen Sahl and Stefan Hell at the Max Planck Institute (MPI) for Multidisciplinary Sciences in Göttingen and the MPI for Medical Research in Heidelberg has succeeded in measuring distances within biomolecules using a light microscope, down to 1 nanometer and with Ångström precision. The intra-molecular
Learn More
X
EN DE
X
X