20.11.2024
Two mechanisms repress cyclin B1 translation to maintain prophase arrest in mouse oocytes
Authors Cheng S, Schuh M Journal Nature Communications Citation Nat Commun. 2024 Nov 20;15(1):10044. Abstract In mammals, oocytes are arrested in prophase of meiosis I for long periods of time. Prophase arrest is critical for reproduction because it allows oocytes to grow to their full size to support meiotic maturation
20.11.2024
Nonlinear receptive fields evoke redundant retinal coding of natural scenes
Authors Karamanlis D, Khani MH, Schreyer HM, Zapp SJ, Mietsch M, Gollisch T Journal Nature Citation Nature. 2024 Nov 20. Abstract The role of the vertebrate retina in early vision is generally described by the efficient coding hypothesis1,2, which predicts that the retina reduces the redundancy inherent in natural scenes3
15.11.2024
Trials and tribulations of cell therapy for heart failure: an update on ongoing trials
Authors Zhang JJ, Pogwizd SM, Fukuda K, Zimmermann WH, Fan C, Hare JM, Bolli R, Menasché P Journal Nature Reviews. Cardiology Citation Nat Rev Cardiol. 2024 Nov 15. Abstract Heart failure (HF) remains a leading cause of mortality, responsible for 13% of all deaths worldwide. The prognosis for patients with
07.11.2024
Nanoparticle start-up receives Lower Saxony Innovation Award
The innovation network Niedersachsen.next has honoured NanoDrug Delivery GmbH with the Lower Saxony Innovation Award 2024 in the ‘Knowledge and Technology Transfer’ category. The spin-off of the Max Planck Institute for Multidisciplinary Sciences (MPI-NAT), the University Medical Center Göttingen (UMG) and the Karlsruhe Institute of Technology (KIT) received the award
06.11.2024
α-Synuclein plastic antibody applied to monitor monomeric structures and discriminate aggregated forms in human CSF
Authors da Silva IS, Cardoso AR, Reimer L, König A, van Riesen C, Outeiro TF, Jensen PH, Sales MGF Journal Biosensors and Bioelectronics Citation Biosensors and Bioelectronics 268 (2025) 116880. Abstract Aggregation of alpha-synuclein (aSyn) occurs in presynaptic neurons and constitutes a key factor for the progression of Parkinson’s disease,
05.11.2024
New results on heart failure: Dysferlin protein protects and shapes the membrane of heart muscle cells
Researchers from the Heart Center of the University Medical Center Göttingen (UMG) led by MBExC member Priv.-Doz. Dr. Sören Brandenburg, have identified a protein that plays a central role in the heart’s adaptation to increased stress. The results of the study were published in the renowned journal ‘Circulation Research’.
04.11.2024
German University Medicine Award goes to research team for the ‘heart patch’
This year, the German University Medicine Award goes to a research team for a globally unique approach: the ‘heart patch’ – a therapy using stem cells to repair the heart muscle and strengthen the heart permanently. The study is a prime example of translational research, from the laboratory to clinical
01.11.2024
A Unifying Approach to Distributional Limits for Empirical Optimal Transport
Authors Hundrieser S, Klatt M, Munk A, Staudt T Journal Bernoulli Citation Bernoulli 30 (4), 2846-2877. Abstract We provide a unifying approach to central limit type theorems for empirical optimal transport (OT). The limit distribution is given by a supremum of a centered Gaussian process, and we explicitly characterize when it