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The inventors (from left), group leader Dr. Ali H. Shaib and Professor Dr. Silvio O. Rizzoli, director of the Department for Neuro- and Sensory Physiology at the University Medical Center Göttingen (UMG). Photo: A. Shaib.

09.10.2024

ONE microscopy: from molecule to 3D structure with conventional microscopy

Researchers at the University Medical Center Göttingen (UMG) have developed a new method that makes it possible for the first time to image the three-dimensional shape of proteins with a conventional microscope. Combined with artificial intelligence, One-step Nanoscale Expansion (ONE) microscopy enables the detection of structural changes in damaged or
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The inventors (from left), group leader Dr. Ali H. Shaib and Professor Dr. Silvio O. Rizzoli, director of the Department for Neuro- and Sensory Physiology at the University Medical Center Göttingen (UMG). Photo: A. Shaib.

09.10.2024

ONE microscopy: from molecule to 3D structure with conventional microscopy

Researchers at the University Medical Center Göttingen (UMG) have developed a new method that makes it possible for the first time to image the three-dimensional shape of proteins with a conventional microscope. Combined with artificial intelligence, One-step Nanoscale Expansion (ONE) microscopy enables the detection of structural changes in damaged or
Learn More
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09.10.2024

One-step nanoscale expansion microscopy reveals individual protein shapes

Authors Shaib AH, Chouaib AA, Chowdhury R, Altendorf J, Mihaylov D, Zhang C, Krah D, Imani V, Spencer RKW, Georgiev SV, Mougios N, Monga M, Reshetniak S, Mimoso T, Chen H, Fatehbasharzad P, Crzan D, Saal KA, Alawieh MM, Alawar N, Eilts J, Kang J, Soleimani A, Müller M, Pape
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