2023

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08.03.2023

Bioinspired Membrane Interfaces: Controlling Actomyosin Architecture and Contractility

Authors Liebe NL, Mey I, Vuong L, Shikho F, Geil B, Janshoff A, Steinem C Journal ACS Applied Materials & Interfaces Citation ACS Appl Mater Interfaces. 2023 Mar 8;15(9):11586-11598. Abstract The creation of biologically inspired artificial lipid bilayers on planar supports provides a unique platform to study membrane-confined processes in
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Outcome of a previous Art of Brain Science event. Photo: Department of Experimental Neurodegeneration, UMG

07.03.2023

The Art of Brain Science

To connect neuroscience from around the world through visual and performance art. Science is founded on the creativity of the human mind, much like art. Spray painting is a versatile technique that is used at a global scale, to convey messages throughout history. In this event, art and neuroscience will
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06.03.2023

Uncovering the molecular link between lead toxicity and Parkinson’s disease

Authors Shvachiy L, Geraldes V, Outeiro TF Journal Antioxidants & Redox Signaling Citation Antioxid. Redox Signal. 39, 321–335. Abstract Significance: Parkinson’s disease (PD) is a progressive neurodegenerative disorder that affects millions around the world. The etiology of PD remains unknown, but environmental and occupational exposures to heavy metals are likely
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06.03.2023

Intermittent Lead Exposure Induces Behavioral and Cardiovascular Alterations Associated with Neuroinflammation

Authors Shvachiy L, Amaro-Leal Â, Outeiro TF, Rocha I, Geraldes V   Journal Cells   Citation Cells. 2023 Mar 6;12(5):818.   Abstract The nervous system is the primary target for lead exposure and the developing brain appears to be especially susceptible, namely the hippocampus. The mechanisms of lead neurotoxicity remain
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Dr. Antoine Huet, MBExC Junior Fellow, Institute for Auditory Neuroscience, UMG. Photo: mbexc.

03.03.2023

In the control room for hearing with light

Optical cochlear implants promise to improve the restoration of hearing in hearing loss and deafness. A Göttingen team of hearing researchers around Antoine Huet have now defined for the first time the biologically plausible range of stimulation parameters for the use of the optical cochlea implant in humans. Published in
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Dr. Antoine Huet, MBExC Junior Fellow, Institute for Auditory Neuroscience, UMG. Photo: mbexc.

03.03.2023

In the control room for hearing with light

Optical cochlear implants promise to improve the restoration of hearing in hearing loss and deafness. A Göttingen team of hearing researchers around Antoine Huet have now defined for the first time the biologically plausible range of stimulation parameters for the use of the optical cochlea implant in humans. Published in
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02.03.2023

A small-angle X-ray scattering study of red blood cells in continuous flow

Authors Burchert JP, Graceffa R, Saldanha O, Burghammer M, Köster S Journal Journal of Synchrotron Radiation Citation J Synchrotron Radiat. 2023 May 1. Abstract Owing to their large penetration depth and high resolution, X-rays are ideally suited to study structures and structural changes within intact biological cells. For this reason,
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28.02.2023

In vitro reconstitution of chromatin domains

Authors Quililan K, Oberbeckmann E, Cramer P, Oudelaar AM   Journal BioRxiv   Citation bioRxiv 2023.02.27.530214.   Abstract The spatial organization of the genome modulates nuclear processes, including transcription, replication, and DNA repair1,2. Eukaryotic genomes are organized into distinct 3D chromatin domains3. However, the molecular mechanisms that drive the formation
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28.02.2023

The multifaceted mitochondrial OXA insertase

Authors Homberg B, Rehling P, Cruz-Zaragoza LD Journal Trends in Cell Biology Citation Trends Cell Biol. 2023 Feb 28:S0962-8924(23)00020-X. Abstract Most mitochondrial proteins are synthesized in the cytosol and transported into mitochondria by protein translocases. Yet, mitochondria contain their own genome and gene expression system, which generates proteins that are
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Prof. Dr. Tobias Moser, Director of the Institute for Auditory Neuroscience, University Medical Center Göttingen and spokesperson of the CRC 1690. Photo: mbexc/spförtner

23.02.2023

ERC Proof of Concept Grant for Tobias Moser

Prof. Dr. Tobias Moser, MBExC spokesperson and Director of the Institute for Auditory Neuroscience at the University Medical Center Göttingen, received an ERC Proof of Concept Grant for his project on „Waveguide-based Cochlear Implants for Optogenetic Stimulation“ (OptoWave). The grant about 150.000 euros enables researchers to bridge the gap between
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