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A mouse egg cell, naturally filled with the protein PADI6 (blue) – a marker and main component of the cytoplasmic lattice. The DNA in the cell nucleus is shown in magenta. Courtesy: Jentoft/Schuh, Max-Planck-Institute for Multidisciplinary Sciences

06.11.2023

Protein stock for the beginning of a new life

How mysterious structures in the egg cell supply the early embryo as protein storage sites   When mammals have offspring, they invest a lot. Unlike fish or frogs, the embryo cannot develop on its own. It has to implant in the uterus, where it is supplied with everything it needs
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A mouse egg cell, naturally filled with the protein PADI6 (blue) – a marker and main component of the cytoplasmic lattice. The DNA in the cell nucleus is shown in magenta. Courtesy: Jentoft/Schuh, Max-Planck-Institute for Multidisciplinary Sciences

06.11.2023

Protein stock for the beginning of a new life

How mysterious structures in the egg cell supply the early embryo as protein storage sites When mammals have offspring, they invest a lot. Unlike fish or frogs, the embryo cannot develop on its own. It has to implant in the uterus, where it is supplied with everything it needs to
Learn More
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06.11.2023

Structure of the transcribing RNA polymerase II-Elongin complex

Authors Chen Y, Kokic G, Dienemann C, Dybkov O, Urlaub H, Cramer P Journal Nature Structural & Molecular Biology Citation Nat Struct Mol Biol. 2023 Nov 6. Abstract Elongin is a heterotrimeric elongation factor for RNA polymerase (Pol) II transcription that is conserved among metazoa. Here, we report three cryo-EM
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06.11.2023

Activation of the integrated stress response rewires cardiac metabolism in Barth syndrome

Authors Kutschka I, Bertero E, Wasmus C, Xiao K, Yang L, Chen X, Oshima Y, Fischer M, Erk M, Arslan B, Alhasan L, Grosser D, Ermer KJ, Nickel A, Kohlhaas M, Eberl H, Rebs S, Streckfuss-Bömeke K, Schmitz W, Rehling P, Thum T, Higuchi T, Rabinowitz J, Maack C, Dudek
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