31.01.2023
Expert in cryo-electron microscopy at the University Medical Center Göttingen receives Consolidator Grant of the European Research Council to investigate the membrane architecture of nerve cells and its pathological alterations in axonopathies. (mbexc/umg) Prof. Dr. Rubén Fernández Busnadiego from the Institute for Neuropathology at the University Medical Center Göttingen (UMG)
31.01.2023
European funding for Rubén Fernández Busnadiego
Rubén Fernández Busnadiego, expert in cryo-electron microscopy at the University Medical Center Göttingen (UMG) and member of the MBExC received a Consolidator Grant of the European Research Council (ERC). The ERC supports his research project ”In situ structural basis of human axonopathies“ (“cryoNERVE“) over five years with a total of
27.01.2023
Cholesterol-Induced Nanoscale Variations in the Thickness of Phospholipid Membranes
Authors Chen T, Ghosh A, Enderlein J Journal Nano Letters Citation Nano Lett. 2023 Jan 27. Abstract Graphene-induced energy transfer (GIET) is a recently developed fluorescence-spectroscopic technique that achieves subnanometric optical localization of fluorophores along the optical axis of a microscope. GIET is based on the near-field energy transfer from
23.01.2023
Towards Unbiased Fluorophore Counting in Superresolution Fluorescence Microscopy
Authors Laitenberger O, Aspelmeier T, Staudt T, Geisler C, Munk A, Egner A Journal Nanomaterials Citation Nanomaterials 2023, 13(3), 459. Abstract With the advent of fluorescence superresolution microscopy, nano-sized structures can be imaged with a previously unprecedented accuracy. Therefore, it is rapidly gaining importance as an analytical tool in the
23.01.2023
Colour images from the shadow of a sample
A research team at the University of Göttingen has developed a new method to produce X-ray images in colour. In the past, the only way to determine the chemical composition of a sample and the position of its components using X-ray fluorescence analysis was to focus the X-rays and scan
23.01.2023
Patient perspectives on the need for improved hearing rehabilitation: A qualitative survey study of German cochlear implant users
Authors Hunniford V, Kühler R, Wolf B, Keppeler D, Strenzke N, Moser T Journal Frontiers in Neuroscience Citation Front Neurosci. 2023 Jan 23;17:1105562. Abstract Background The electrical cochlear implant (eCI) partially restores hearing in individuals affected by profound hearing impairment (HI) or deafness. However, the limited resolution of sound frequency
21.01.2023
Single-cell transcriptomics reveal extracellular vesicles secretion with a cardiomyocyte proteostasis signature during pathological remodeling
Authors Schoger E, Bleckwedel F, Germena G, Rocha C, Tucholla P, Sobitov I, Möbius W, Sitte M, Lenz C, Samak M, Hinkel R, Varga ZV, Giricz Z, Salinas G, Gross JC, Zelarayán LC Journal Communications Biology Citation Commun Biol. 2023 Jan 21;6(1):79. Abstract Aberrant Wnt activation has been reported in failing
21.01.2023
Simulation of Complex Biomolecular Systems: The Ribosome Challenge
Authors Bock LV, Gabrielli S, Kolá MH, Grubmüller H Journal Annual Review of Biophysics Citation Annu. Rev. Biophys. 2023. 52:15.1–15.30. Abstract Large biomolecular systems are at the heart of many essential cellular processes. The dynamics and energetics of an increasing number of these systems are being studied
19.01.2023
Graded optogenetic activation of the auditory pathway for hearing restoration
Authors Mittring A, Moser T, Huet AT Journal Brain Stimulation Citation Brain Stimul. 2023 Jan 23:S1935-861X(23)01673-X. Abstract Optogenetic control of neural activity enables innovative approaches to improve functional restoration of diseased sensory and motor systems. For clinical translation to succeed, optogenetic stimulation needs to closely match the coding properties of
18.01.2023
Impact of the Euro 2020 championship on the spread of COVID-19
Authors Dehning J, Mohr SB, Contreras S, Dönges P, Iftekhar EN, Schulz O, Bechtle P, Priesemann V Journal Nature Communications Citation Nat Commun 14, 122 (2023). Abstract Large-scale events like the UEFA Euro 2020 football (soccer) championship offer a unique opportunity to quantify the impact of gatherings on the spread