May

Home >> 2022 >> May >> Page 3
Feature image not available
03.05.2022

α-Synuclein Impacts on Intrinsic Neuronal Network Activity Through Reduced Levels of Cyclic AMP and Diminished Numbers of Active Presynaptic Terminals

Authors Leite K, Garg P, Spitzner FP, Guerin Darvas S, Bähr M, Priesemann V, Kügler S Journal Frontiers in Molecular Neuroscience Citation Front Mol Neurosci. 2022 May 3;15:868790. Abstract α-synuclein (α-Syn) is intimately linked to synucleinopathies like Parkinson’s disease and dementia with Lewy bodies. However, the pathophysiological mechanisms that are
Learn More

The figure shows a cell with excessive alpha-synuclein (left) compared to a cell, where alpha-synuclein was genetically switched off (right). The cell nucleus is colored blue, the protein alpha-synuclein yellow.© Felipe Opazo / UMG

02.05.2022

Possible biomarker for Parkinson’s discovered using new MRI method

Certain metabolic products are suitable as indication for Parkinson’s disease. Researchers and MBExC members at the Max Planck Institute (MPI) for Multidisciplinary Sciences, the University Medical Center Göttingen (UMG), and the German Center for Neurodegenerative Diseases (DZNE) have used this insight in a first step to develop a new diagnostics
Learn More
Feature image not available
02.05.2022

HAX1-dependent control of mitochondrial proteostasis governs neutrophil granulocyte differentiation

Authors Fan Y, Murgia M, Linder MI, Mizoguchi Y, Wang C, Łyszkiewicz M, Ziȩtara N, Liu Y, Frenz S, Sciuccati G, Partida-Gaytan A, Alizadeh Z, Rezaei N, Rehling P, Dennerlein S, Mann M, Klein C Journal Journal of Clinical Investigation Citation J Clin Invest. 2022 May 2;132(9):e153153. Abstract The relevance
Learn More
Feature image not available
02.05.2022

Cellular and mitochondrial mechanisms of atrial fibrillation

Authors Jung P, Seibertz F, Fakuade FE, Ignatyeva N, Sampathkumar S, Ritter M, Li H, Mason FE, Ebert A, Voigt N. Journal Basic Research in Cardiology Citation Basic Res Cardiol. 2022 May 2;117(1):5. Abstract Dilated cardiomyopathy (DCM) is a major risk factor for heart failure and is associated with the
Learn More
X
EN DE
X
X