The cartoon illustration shows a part of the apoferritin protein (yellow) with a tyrosine side chain highlighted in grey. The amino acid tyrosine consists of several atoms that are individually recognizable in the structure (red grid structures). © Holger Stark / MPI-BPC

World record resolution in cryo electron microscopy

Holger Stark and his team at the Max Planck Institute (MPI) for Biophysical Chemistry have broken a crucial resolution barrier in cryo electron microscopy. The scientists succeeded in observing single atoms in a protein structure and taking the sharpest images ever with this method. Such unprecedented details are essential to understand how proteins perform their work in the living cell or cause diseases. The technique can in future also be used to develop active compounds for new drugs.

Please find the full MPI-BPC press release here.