Prof. Dr. Johannes Letzkus from the Institute for Physiology I, University of Freiburg will talk about “Top-down control of neocortical threat memory”

Abstract
Accurate perception of the environment is a constructive process that requires integration of external bottom-up sensory signals with internally-generated top-down information reflecting past experiences and current aims. Decades of work have elucidated how sensory neocortex processes physical stimulus features. In contrast, examining how memory-related top-down information is encoded and integrated with bottom-up signals has long been challenging. Here, I will discuss our recent work identifying the outermost layer 1 of neocortex as a central hotspot for processing of experience-dependent top-down information during threat perception, one of the most fundamentally important forms of sensory perception.

Chairs: Tobias Moser and Thomas Mager