Cells cultured in the laboratory (cyan). Artificial viruses that mimic SARS-CoV-2 (magenta) infect the cells via ACE2 and neuropilin-1. Source: DZNE/ Liliana Pedro-Domingues

Coronavirus: Study finds further door opener into the cell

The coronavirus SARS-CoV-2 is known to infect cells via the receptor ACE2. An international research team under German-Finnish coordination has now identified neuropilin-1 as a factor that can facilitate SARS-CoV-2 entry into the cells’ interior.
Neuropilin-1 is localized in the respiratory and olfactory epithelia, which could be a strategically important localization to contribute to SARS-CoV-2 infectivity and spreading. Experts from the German Center for Neurodegenerative Diseases (DZNE), Technical University of Munich (TUM), University Medical Center Göttingen (UMG), University of Helsinki and other research institutions now published their findings in the journal “Science”.

Please find the full DZNE press release here.