Calcium-Triggered Membrane Fusion

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05.01.2019

A dual-AAV approach restores fast exocytosis and partially rescues auditory function in deaf otoferlin knock-out mice

Authors Al-Moyed H, Cepeda A P, Jung S, Moser T, Kugler S, Reisinger E Journal EMBO Molecular Medicine Citation EMBO Mol Med (2019) 11: e9396. Abstract Normal hearing and synaptic transmission at afferent auditory inner hair cell (IHC) synapses require otoferlin. Deafness DFNB9, caused by mutations in the OTOF gene
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